Bioinformatics competency has become a key element in much of contemporary biology. The increasing potential that is to be realized with modern technologies, such as 'next-generation' sequencing, parallel and 'cloud' computing, and continually increasing data banks, requires a fundamental understanding of bioinformatics concepts and applications. On par with the complexity of biological inquiry...

aim : evaluation of biological characteristics of 13 identified proteins of patients with cirrhotic liver disease is the main aim of this research.   background : in clinical usage, liver biopsy remains the gold standard for diagnosis of hepatic fibrosis. evaluation and confirmation of liver fibrosis stages and severity of chronic diseases require a precise and noninvasive biomarkers. since the...

the object of this cross sectional study was to determine the hcv subtype 3a envelope protein binding affinity with human leukocyte antigen. envelope 1 (e1) protein is one of the structural proteins responsible for entering the cells through the receptors. the binding affinity of e1 protein epitopes to the selected human leukocyte antigen (hla) class i alleles was investigated using the compute...

With the development of human genome projects ( HGP) in the world, a mass of genetic information is generated. Now there are hundreds of different kinds of important bioinformatics databases in the world. How to unify the bioinformatics database from different countries has become an important issue in Bioinformatics. In this paper, we present a data integration program based on Web Services of...