Advances in medical imaging and image processing are paving the way for personalised cardiac biomechanical modelling. Models provide the capacity to relate kinematics to dynamics and-through patient-specific modelling-derived material parameters to underlying cardiac muscle pathologies. However, for clinical utility to be achieved, model-based analyses mandate robust model selection and paramet...

The extrapolation of biological damage from a biomechanical model requires that a closed-form mathematical damage threshold function (DTF) be included in the model. A DTF typically includes a generic load variable, being the critical load (e.g., pressure, strain, temperature) causing irreversible tissue or cell damage, and a generic time variable, which represents the exposure to the load (e.g....

Biomechanical Signaling Physarum polycephalum, a slime mold with one cell and no brain, is remarkable new model for understanding basal cognition. Its living material deforms its own structure to interact the objects around it. In article number 2008161, Michael Levin co-workers show that senses strain in substrate, using biomechanical signaling assess environment express preferences as directi...

BACKGROUND With the aging of the population, degenerative scoliosis (DS) incidence rate is increasing. In recent years, increasing research on this topic has been carried out, yet biomechanical research on the subject is seldom seen and in vitro biomechanical model of DS nearly cannot be available. The objective of this study was to develop and validate a complete three-dimensional finite eleme...