Chromatin regulation is a fundamental mechanism underlying stem cell pluripotency, differentiation, and the establishment of cell type-specific gene expression profiles. To examine the role of chromatin regulation in stem cells in vivo, we study regeneration in the freshwater planarian Schmidtea mediterranea. These animals possess a high concentration of pluripotent stem cells, which are capabl...

Biscogniauxia species are known as fungal trunk pathogens on various tree in the world. During a survey of diseases fruit trees conducted Iran, branch dieback was observed almond Kerman province (in Southeast Iran). Evaluation symptomatic branches revealed wood discoloration cross-sections and presence fruiting bodies an ascomycete fungus their bark. A total 31 isolates were obtained, 13 recove...

www.sciencemag.org SCIENCE VOL 332 13 MAY 2011 757 COVER Composite confocal image of an adult planarian (Schmidtea mediterranea) showing a growing colony of dividing cells (red) that initiated from a single, pluripotent stem cell called a clonogenic neoblast (cNeoblast). The ~1-millimeter-long animal is visualized with differential interference contrast microscopy and nuclear staining (blue). T...