Bisphenol A or BPA-based epoxy resins are widely used in the manufacture of commercial products, including dental resins, polycarbonate plastics, and the inner coating of food cans. BPA is a precursor to the resin monomer Bis-GMA. During the manufacturing process of Bis-GMA dental sealants, Bisphenol A (BPA) might be present as an impurity or as a degradation product of Bis-DMA through esterase...

The use of pit and fissure sealants has been reported to increase exposure to xenoestrogens. Because these estrogen-mimics are suspected of having many deleterious effects in animals, and perhaps humans, several types of studies were undertaken by our Biocompatibility Group. We confirmed that bisphenol A (BPA) and bisphenol A dimethacrylate (BPA-DM) have proliferative effects in cells with high...

CONTEXT Dental sealants and composite filling materials containing bisphenol A (BPA) derivatives are increasingly used in childhood dentistry. Evidence is accumulating that BPA and some BPA derivatives can pose health risks attributable to their endocrine-disrupting, estrogenic properties. OBJECTIVES To systematically compile and critically evaluate the literature characterizing BPA content o...

Bisphenol-A (BPA) is a component of a coating material in can packaging and is known to leach out to the canned food. It is a known endocrine disruptor, carcinogen and mutagen hence detection and control of BPA should be a concern to protect the consumers. This study aims to develop a molecularly imprinted polymer (MIP) for the molecular recognition of BPA. This paper presents the synthesis and...

The endocrine disrupting chemical bisphenol A (BPA) is widely used in the production of polycarbonate plastics and epoxy resins. The use of BPA-containing products in daily life makes exposure ubiquitous, and the potential human health risks of this chemical are a major public health concern. Although numerous in vitro and in vivo studies have been published on the effects of BPA on biological ...

What is bisphenol A? Bisphenol A (BPA) is a chemical used primarily for the production of polycarbonate plastics and epoxy resins. Some 3 billion kilos of BPA are produced worldwide and the use of this chemical is so ubiquitous that it has been detected in the urine of 93 per cent of the population over 6 years of age (Welshons et al., 2006; Calafat et al., 2005). A recent study found that BPA ...

Bisphenol-A (BPA) has been considered as an endocrine disrupting chemical (EDC) because it can exert estrogenic properties. For bisphenol-S (BPS) and bisphenol-F (BPF) that are BPA analogs and substitutes, their risk to estrogen-dependent cancer has been reported rarely compared with the numerous cases of BPA. In this study, we examined whether BPA, BPS, and BPF can lead to the proliferation, m...

OBJECTIVES To estimate the association between serum bisphenol A and premature thelarche in female infants aged 4-mo to 2-y. METHODS A total of 251 female infants (aged 4 mo to 2 y) with premature thelarche and 33 healthy age-matched control subjects were analyzed. All participants underwent physical examination and serum bisphenol A was measured by ultra-performance liquid chromatography tan...

Bisphenol A (BPA) is a synthetic compound widely used in types of consumer goods and medical tools. It has been shown that BPA acts as an endocrine disruptor chemical casuing negative impact on reproductive functions. The present study used an in vitro approach to assess estrogenic transcriptional activity of BPA as a rapid and sensitive method. The cultured pieces of hepatic tissue of goldfish...

Bis-GMA and epoxy resins are known to cause allergic reactions in some patients. The purpose of this research was to investigate the sensitizing capacity, cross-reactivity and antigenic determinants of bisphenol A (BPA), a major constituent of Bis-GMA and BPA type epoxy resins. Anti-BPA antibodies were prepared from mice injected with BPA-ovalbumin conjugates (BPA-OVA), and the reactions of the...