Bisphenol A (BPA) is an endocrine disruptor with estrogenic properties that can adversely affect meiotic spindle assemblies. Our data indicate that BPA exposure in female patients may interfere with oocyte quality during IVF, as suggested by the inverse association between serum unconjugated BPA concentration and normal fertilization.

The chromatographic method used to monitor the Bisphenol-A manufacturing process was improved using Agilent RRHT Eclipse XDB-C18 columns. These columns use 1.8-μm particles versus conventional 3.5-μm or 5-μm particles. The improved method allowed seven times faster analyses, improved resolution, and higher sensitivity. Introduction Bisphenol-A (Figure 1) is a highly versatile material used to m...

BACKGROUND Bisphenol A (BPA) is a high-production-volume chemical associated with a wide range of health outcomes in animal and human studies. BPA is used as a developer in thermal paper products, including cash register receipt paper; however, little is known about exposure of cashiers to BPA and alternative compounds in receipt paper. OBJECTIVE We determined whether handling receipt paper r...

Target molecule-responsive hydrogels with β-cyclodextrin (β-CD) were prepared via molecular imprinting using bisphenol A (BPA) as a template. BPA-imprinted hydrogels showed greater shrinkage than non-imprinted hydrogels because CD ligands arranged at suitable positions formed CD-BPA-CD complexes that acted as crosslinks.

Abstract Background Bisphenol A (BPA) causes environmental pollution and is used as a natural antioxidant to protect against chemical side-effects. Costus well-known medicinal plant containing several biologically active compounds. We investigated the protective effects of costus extract toxic BPA in rat testes. Results Biochemical immunohistochemical investigations revealed that bisphenol redu...

Label-free detection of bisphenol A based on the impedance measurement was achieved with an impedimetric immunosensor. The immunosensor was fabricated by the covalent bond formation between a polyclonal antibody and a carboxylic acid group functionalized onto a nano-particle comprised conducting polymer. By using a commercial reagent 4,4-bis(4-hydroxyphenyl) valeric acid (BHPVA), which has an a...

OBJECTIVE To investigate associations between serum bisphenol A (BPA) concentrations and follicular response to exogenous ovary stimulation. DESIGN Fasting serum was prospectively collected on the day of oocyte retrieval and assessed for unconjugated BPA using high-performance liquid chromatography with Coularray detection. Multivariable linear regression and negative binomial regression were...

A molecularly imprinted polymer (MIP), obtained by precipitation polymerisation with 4-vinylpyridine as the functional monomer, ethylene glycol dimethacrylate as cross-linker, and bisphenol-A (BPA) as template, was prepared. The binding site configuration of the BPA-MIP was examined using Scatchard analysis. Moreover, the behaviour of the BPA-MIP for the extraction of several phenolic compounds...

A highly sensitive and selective method for simultaneous determination of some hydroxyl group-containing endocrine disruptors, including bisphenol A (BPA), bisphenol B (BPB), bisphenol E (BPE), bisphenol F (BPF) and 4-nonylphenol (4-NP), was developed. The method consists of precolumn derivatization of the analytes, solid-phase extraction (SPE) and subsequent chromatographic analysis by high-pe...

Experimental investigations showed that bisphenol A (BPA) affects the male reproductive tract. The male hormones level, androgen`s receptors, male reproductive organs, the testes, the epididymis, the seminal vesicles, the prostate and sperm production are affected by this substance. The objective of this study is to present the effects of bisphenol administration upon spermatogenesis at mice. D...