Background: Bladder cancer ranks ninth in world-wide cancer incidence and is 2.5-4 times more common in men, and painless gross hematuria is its typical clinical symptom. Cystoscopy is used to evaluate the cause of hematuria in bladder while the use and reliability of ultrasonography is questionable for this purpose. Therefore, the aim of this study was to compare abdominal ultrasonography and ...

BACKGROUND Pim-1 is a serine-threonine kinase which promotes early transformation, cell proliferation and cell survival during tumorigenesis. Several studies have demonstrated that Pim-1 kinase play a role in different cancer types, however, the function of Pim-1 in bladder cancer is poorly understood. METHODS Expression and localization of Pim-1 in human normal and malignant bladder specimen...

This is a letter to the editor on discussion COVID-19 vaccine and bladder cancer.

Objective To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper urothelial [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk markers geographical variation. Patients Methods This was an international multicentre prospective observational study. We included aged ?16 years, suspected cancer. a kn...

BACKGROUND The application of microRNAs (miRNAs) as potential biomarkers and therapy targets has been widely investigated in many kinds of cancers. The discovery of tumor associated miRNAs in serum of patients supported the use of plasma/serum miRNAs as noninvasive means of cancer detection. However, the aberrant expression of miRNAs in bladder cancer patients and their intensive roles and mech...

BACKGROUND Previous studies have shown that the expression level of γ-synuclein (SNCG) is associated with progression of many different malignant tumors. In this study, we discuss and assess the prognostic ability of SNCG in bladder cancer. MATERIAL AND METHODS Medical records (2005-2013) were retrospectively reviewed for the population of interest. SNCG expression was identified immunohistoc...

We have previously reported that the expression of periostin mRNA is significantly repressed in human bladder cancer tissues, and that periostin plays a role as a suppressive factor for invasion and metastasis in the progression of human bladder cancers. In this study, to clarify the role of alternative splicing of periostin in human bladder carcinogenesis, we examined the expression of wild-ty...

Abstract Background Urinary bladder tumors are the most common type of detected in patients with gross hematuria. Multidetector computed tomography (MDCT) is an accurate method for detecting lesions. This review aims to describe features MDCT and possible values distinguishing these lesions bladder. Main body In this review, we discuss role evaluation cancer a broad spectrum lesions, including ...

Although our most recent studies have identified Isorhapontigenin (ISO), a novel derivative of stilbene that isolated from a Chinese herb Gnetum cleistostachyum, for its inhibition of human bladder cancer growth, nothing is known whether ISO possesses an inhibitory effect on bladder cancer invasion. Thus, we addressed this important question in current study and discovered that ISO treatment co...