stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. they are found in multicellular organisms. in mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. in ad...

Background: Exposure to environmental toxins such as organophosphates poses a great threat to the health of the public. In this work, we investigated the effects of continuous exposure to dichlorvos (DDVP) on kidney function and hematological parameters, and the possible antidote activity of Nigella sativa oil (NSO). Methods: This research was conducted in 2016, at The Animal Holding and Resea...

abstractbackground: fetal bovine serum (fbs) is widely used in cell culture laboratories,risk of zoonotic infections and allergic side effects create obstacles for its use inclinical trials. therefore, an alternative supplement with proper inherent growthpromotingactivities is demanded.objective: to find fbs substitute, we tested human umbilical cord blood serum(hucs) for proliferation of human...

Background: Dendritic cells (DCs) are the most potent stimulators of primary T cell responses and play a key role in immune reactions after stem cell transplantation. Very little is known about the cord blood (CB) dendritic cells and their potential involvement in the low incidence and lower severity of acute graft-versus-host disease after CB transplantation.   Objectives: The aim of this stud...

Background: The development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. Also, Autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. We studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in Ilam province...

background: mesenchymal stromal cells (mscs) are employed in various different clinical settings in order to modulate immune response. human autologous and allogeneic supplements including platelet derivatives such as platelet lysate (pl), platelet-released factors (prf) and serum are assessed in clinical studies to replace fetal bovine serum (fbs). the immunosuppressive activity and multi-pote...

backgrounds: thyroid hormones play an important physiological role in human metabolism. erythrocyte abnormalities are frequently associated with thyroid disorder. however, they are rarely investigated and related to the subclinical and primary hypothyroidism in kashmiri patients. in this study an attempt was made to study hematological parameters in untreated and treated subclinical hypothyroid...

in this paper we present a method related to extracting white blood cells (wbcs) from blood microscopic figures and recognizing them and counting each kind of wbcs. in this method, first we extract the white blood cells from other blood cells by rgb color system's help. in continuance, by using the features of each kind of globules and their color scheme, we extract a normalized feature vector,...

the aim of this study was to assess the predictive effect of the ebmt risk score on the outcomes of allogeneic stem cell transplantation in a relatively homogenous group of acute myelogenous leukemia (aml) patients regarding the occurrence of acute and chronic graft versus host disease (gvhd). this historical cohort study included adult patients (≥ 15 years old) with aml (n=363) who received al...