Background Transfusion-transmitted malaria is undoubtedly a potential health hazard for blood recipients. Egypt is still on the prevention of reintroduction phase of malaria control program. Fayoum Governorate is considered one of the high-risk foci in Egypt due to its geology. However, no studies have been reported to evaluate the current status of subclinical Plasmodium infection based on sen...

The main challenge facing the team of Regional Center for Transfusion Hematology Varna (RCTH Varna) during pandemic COVID-19 stems from need to quickly adapt processes blood donation and supply components hospitals. Most similar current is SARS-CoV epidemic in 2003, which WHO noted that no cases infection due transfusion components, risk transmission this new virus, although theoretical, cannot...

1Department of Transfusion Medicine, Warren Grant Magnuson Clinical Center; 2Molecular Hematology Section, National Institute of Diabetes, Digestive and Kidney Diseases; 3Hematology Branch, National Heart, Lung and Blood Institute; 4Experimental Transplantation and Immunology Branch, National Cancer Institute; 5Laboratory of Host Defenses, National Institute of Allergy, Immunology and Infectiou...

BACKGROUND Few studies have examined the impact of balanced resuscitation in pediatric trauma patients requiring massive transfusions. Adult data may not be generalizable to children. METHODS Retrospective analysis assessed patients seen at a level I trauma center between 2003 and 2010 aged ≤18 years requiring massive packed red blood cell (PRBC) transfusion, defined as transfusion of ≥50% to...

1Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, MD, United States of America; 2University of Campinas, Campinas, Brazil; 3Heaton Dx Consulting, San Francisco, CA; 4American Red Cross, Philadelphia, PA; 5Cedars Sinai Medical Center, Los Angeles, CA; 6Brigham and Women's Hospital, Boston, MA, United States of America; 7EFS Île-de-France, Creteil,...

BACKGROUND Perioperative red blood cell transfusion is associated with adverse outcomes after cardiac operations. Although restrictive transfusion protocols have been developed, their safety and efficacy are not well demonstrated, and considerable variation in transfusion practice persists. We report our experience with a restrictive transfusion protocol. METHODS We analyzed the outcomes in 4...

Introduction: The thalassamias refer to a diverse group of hemoglobin disorders characterized by a reduced synthesis of  one or more of globin chains (α,β, γ, δβ,γδβ, δ and εγδβ).The main cure available today for thalassamia is bone marrow transplantation (BMT)  from compatible donor.On December 3, 1981 a 14-month-old child with β-thalassemia major recieved BMT from his HLA-identical sister in...

background: beta thalassemia gene mutations are among common mutations in southwest iran. however, hemoglobin e (hb e) and hb e/β⁰ thalassemia account for a small number of hemoglobinopathies in iran. this is the first study to directly address the existence of hb e and consequently hb e/β⁰ thalassemia in southwest iran. methods: this retrospective study discovered seven cases of hb e/β⁰ thalas...

iron is a pro-oxidant cofactor that may be linked to atherosclerosis progression. free iron catalyzes the generation of free radicals and free radicals promote the oxidation of lipids. reduction of body iron stores secondary to blood donation has been hypothesized to reduce lipid peroxidation. the aim of this study was to evaluate the association between blood donation and antioxidant enzymes a...