currently autografts are gold standards for craniomaxillofacial bone regeneration. but autografts have some limitations. bone tissue engineering has been introduced to overcome these limitations. it consist three components: stem cells, growth factor, and scaffold. scaffold provides an environment for bone growth and simplifies cell adhesion, differentiation and proliferation. in this review, a...

background: paget's disease is a focal bone disorder manifested as bone overgrowth and disrupted bone integrity as a result of accelerated bone remodelling rate. rarely, paget's disease of the base of the skull results in hydrocephalic dementia, and the triad of normal pressure hydrocephalus syndrome is a much more scarce entity. case report: herein, we report an elderly woman who presented in ...

Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine which controls the differentiation and growth of hematopoietic cells in the bone marrow. We report a severe aplastic anemia (SAA) patient with false-negative 99mTc sodium phytate bone marrow imaging findings under concurrent G-CSF therapy. The first bone marrow imaging showed a normal bone marrow activity. However, the bo...

introduction: osteoporosis and periodontal diseases are both multifactorial and are mostly associated with aging. the aim of this study was to evaluate the relationship between osteoporosis and periodontal diseases. materials and methods: in this analytical/cross-sectional study, periodontal examinations were carried out on 98 women who had undergone bone mass densitometry. of these cases, cons...

conclusions epo injection into the site of tibiofibular fractures may possibly accelerate healing. background erythropoietin (epo), in addition to its function as an erythropoiesis regulator has a regenerative activity on some nonhematopoietic tissues. animal studies have suggested a role for erythropoietin in bone healing. objectives the present study aimed to evaluate the effects of local epo...

reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. plasma rich in growth factors (prgf) offers a new and potentially useful adjunct to bone substitute materials in bone reconstructive surgery. this study was carried out to investigate the influence of prgf and fibrin membrane on regeneration of bony defects with and without deprotein...

pre-implant disease is an inflammatory process that affects the surrounding tissues of a functional osseointegrated implant. it is usually the result of a disequilibrium between the micro-flora and the defense system. this case reports a 57-year-old man with unusual bone loss around dental implants. this was an unusual case of peri-implantitis that occurred only in the implants on one side of t...

objectives: implant primary stability is one of the important factors in achieving implant success. the osteotome technique may improve primary stability in patients with poor bone quality. the aim of this study was to compare implant stability using two different techniques namely osteotome versus conventional drilling in the posterior maxilla. materials and methods: in this controlled randomi...

statement of problem: glucocorticoid-induced osteoporosis is characterized by a decrease in osteoblast numbers and a marked impairment of new bone formation. purpose: the ain of present study was to evaluate the effect of methylprednisolone acetate on bone metabolism and bone mineral density in rats. materials and methods: eighteen male sprague dawley rats (8 weeks old, weighting 180 gm) were r...