AIMS AND BACKGROUND In hematologic malignancies, bone marrow aspiration is considered complementary to bone marrow biopsy for the detection of tumor infiltration. The present study evaluated the accuracy of bone marrow aspiration and the relative contributions of bone marrow aspiration and bone marrow biopsy in detecting bone marrow involvement by non-Hodgkin lymphomas. METHODS AND STUDY DESI...

primary myeloid sacrom (ms) is a rare tumor and even more rare in multiple organs with no evidence of bone marrow involvement. this report describes an unusual case of a 19-year-old male presenting scrotal ms with a history of subconjunctival ms, 5 months ago. bone marrow biopsies showed no evidence of acute leukemia. despite radiotherapy for first involvement and chemotherapy for second presen...

Citral is a major constituent of Cymbopogon citratus or lemongrass oil. The anti-clastogenic effect of citral (20 mg/kg) was tested against the known mutagens cyclophoshamide, mitomycin-C and nickel metal (NiCl2) in mice. Micronucleus (MN) frequency was evaluated in both bone marrow and peripheral blood erythrocytes. The sampling was done after 24 h, 48 h and 72 h of clastogen treatment. Result...

Background: Hematological disorders are found commonly in the general population existing on both ends of spectrum with minute like iron deficiency anemia to as severe bone marrow infiltration Objective: To assess frequency hematological malignancies based bone-marrow aspiration and trephine biopsy patients presenting tertiary care hospital Methodology: The current study was cross-section descr...

ABSTRACT We analyzed the mechanisms underlying enhanced IgA production in cells of Peyer's patch via membrane vesicles derived from Lactobacillus sakei subsp. NBRC 15893. Depletion CD11c+ suppressed mediated by vesicles. Meanwhile, stimulation bone-marrow–derived dendritic with increased gene expression inducible nitric oxide synthase, retinaldehyde dehydrogenase 2, and several inflammatory cyt...

Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...

High-dose chemotherapy and autologous stem cell transplantation (SCT) have become an effective care for many patients with hematological malignancies. Harvesting the stem cells is one the most important parts of SCT. The two most commonly used mobilization regimens are the use of granulocyte colony-stimulating factor (G-CSF) or G-CSF plus chemotherapy. However, about 10-30% of patients are unab...

High-dose chemotherapy and autologous stem cell transplantation (SCT) have become an effective care for many patients with hematological malignancies. Harvesting the stem cells is one the most important parts of SCT. The two most commonly used mobilization regimens are the use of granulocyte colony-stimulating factor (G-CSF) or G-CSF plus chemotherapy. However, about 10-30% of patients are unab...