Bone scintigraphy being a highly sensitive modality is useful in the detection of skeletal metastases in cancer patients. The procedure does not pose any radiation risks to the patients. To improve the specificity of the modality, proper patient selection is important. This article explores the application of bone scintigraphy in detection of metastatic cancer with an insight about patient sele...

Bone scintigraphy of metastatic lesion on 128 patients with prostatic cancer were classified according to the proposal by Soloway et al (Cancer, 61; 195-202, 1988). Since all patients received endocrine therapy, the response to therapy and survival were examined in relation to bone lesion. In extent of disease (EOD) 1, main metastatic lesions were located in the pelvis, lumbar spine, and with i...

Bacterial orbital cellulitis is an infection of the soft tissues behind the orbital septum. Cellulitis is seen as a poorly defined area of increased CT density or T2 signal intensity within the fat. There is an amorphous enhancement following contrast infusion. Radiolabeled leukocytes or granulocytes are now established widely as a means of localizing various forms of inflammatory disease and i...

thallium 201 whole body scintigraphy was performed in a 30 year old patient with diffuse osseous metastatic disease secondary to glioblastoma multiforme. multiple sites of thallium uptake correlated with the findings on serial bone scans and radiographs. bone biopsy of a lower lumbar vertebra confirmed that the metastases were of glial origin.

Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and parathyroid hormone (PTH) who was referred to our department for a parathyroid scan with SPECT/ CT. Parathyroid scintigraphy showed a focus of i...

Incidental extra-osseous uptake of 99mTc-MDP on bone scintigraphy has been frequently reported in the literature; however, calcification of the psoas muscle is a rare condition, which has been reported on magnetic resonance (MR) and computed tomography (CT) imagings. Here we report a 67-year-old woman with acute paraplegia and low back pain who was referred for a 99mTc-MDP...

a 29- year old female with bone pain and history of precocious puberty was referred for bone scintigraphy. on physical examination café au lait macular spots were noted on her neck, buttocks and left leg. bone scan showed multiple areas of intense increased activity which was in favour of polyostotic fibrous dysplasia. considering the presence of polyostotic fibrous dysplasia, precocious pubert...

Current treatment of metastatic bone prostate cancer with Docetaxel chemotherapy per CHAARTED trial is standard of care. Timing of CT and bone scintigraphy for evaluation of successful treatment of lytic lesions is not available in the literature. We present a case of a 70 year old male with PSA of 586 and wide spread metastatic bone lytic lesions, who underwent androgen deprivation therapy and...

Soft tissue uptake of Tc-99m labeled bone seeking agents, such as Tc-99m 3,3-diphosphono-1,2-propanedicarboxylic acid (DPD), is commonly seen in clinical practice, even though bone scintigraphy is mainly used to detect bone disease. However, gastric uptake of bone agents in patients with gastric cancer is very rare. And it has been reported that calcified gastric adenocarcinoma appears in only ...

A 14-year-old child was diagnosed with primitive neuroectodermal tumor (PNET) of pelvis. Baseline 99mTc-methtylene diphosphonate (MDP) bone scintigraphy done to know the extent of the disease, although of suboptimal quality, revealed involvement of right hemipelvis (A, arrowhead) (Fig. 1). Also, there was a focus of increased radiotracer uptake in the occipital bone (B, arrow). Since the patien...