UNLABELLED Planar 131I scintigraphy is routinely used to detect radioiodine-avid metastases of differentiated thyroid carcinoma (DTC). However, the modality has limitations, such as low sensitivity and lack of anatomic landmarks. We investigated whether SPECT with integrated low-dose CT may have additional value over planar imaging in detecting residue and metastases in DTC patients. METHODS ...

Introduction: Various bone palliative therapeutic agents have been developed and widely used for bone metastasis such as 153Sm-EDTMP. In this study, production, quality control and biodistribution studies of a newly developed therapeutic compound have been presented followed by imaging studies in wild-type rodents. Methods: 153Sm-TTHMP was prepared starting from 153<...

introduction: nowadays various bone pain palliative therapeutic agents have been developed for bone metastases. among those, 153sm-ethylenediamine tetramethylene phosphonic acid (153sm-edtmp) is the major therapeutic agent which is widely used in the world. in this study, production, quality control and biodistribution studies of this therapeutic radiopharmaceutical have been presented and foll...

skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. the skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. the patients with skull meta...

Skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. The skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. Focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. The patients with skull meta...

OBJECTIVE To investigate the value of integrin αvβ3 targeted imaging with 99mTc-HYNIC-PEG4-E[PEG4-c(RGDfk)]2 (99mTc-3P-RGD2) as a radiotracer in dectecting osteolytic bone metastases. METHODS This is a retrospective study involving a cohort of 69 consecutive patients including 59 with lung cancer and 10 with other cancers. Patients were required to receive whole body scan (WBS) and regional S...