The precise localisation of osteoarthritic changes is crucial for selective surgical treatment. Single photon-emission CT-CT (SPECT-CT) combines both morphological and biological information. We hypothesised that SPECT-CT increased the intra- and interobserver reliability to localise increased uptake compared with traditional evaluation of CT and bone scanning together. We evaluated 20 consecut...

UNLABELLED Endovenous bisphosphonate therapy seems associated with osteonecrosis of the jaw. The aim of this study was to evaluate the additional diagnostic value of hybrid SPECT/CT in 99mTc-methylene diphosphonate 3-phase bone scintigraphy of osteonecrosis of the jaw in bisphosphonate-treated patients. METHODS We studied 15 patients (12 women and 3 men) with extraoral tumors affected by lyti...

Bone tissue engineering shows good prospects for mandibular reconstruction. In recent studies, prefabricated tissue-engineered bone (PTEB) by recombinant human bone morphogenetic proteins (rhBMPs) applied in vivo has found to be an effective alternative for autologous bone grafts. However, the optimal time to transfer PTEB for mandibular reconstruction is still not elucidated. Thus, here in an ...

Endovenous bisphosphonate therapy seems associated with osteonecrosis of the jaw. The aim of this study was to evaluate the additional diagnostic value of hybrid SPECT/CT in 99mTc-methylene diphosphonate 3-phase bone scintigraphy of osteonecrosis of the jaw in bisphosphonate-treated patients. Methods: We studied 15 patients (12 women and 3 men) with extraoral tumors affected by lytic bone metas...

PURPOSE To evaluate the role of single photon emission computed tomography (SPECT) bone scan for the diagnosis of knee lesions in routine clinical practice. METHODS 40 consecutive case records were examined in patients who underwent a SPECT scan prior to knee arthroscopy in routine clinical practice. The accuracy of clinical examination, SPECT scan results, and arthroscopic findings (as the g...

The skeleton is a metabolically active organ that undergoes continuous remodelling throughout life. Normal healthy bones are dynamic structures with inherent basal levels of turnover sustained by balanced osteoblastic and osteoclastic activity. Increased bone turnover (ie osteoblastic activity) is the central mechanism of attempts at bone healing in case of any insult, whether it is benign or m...

Bone scintigraphy is an extremely valuable technique in diagnosis and treatment planning for patients with condylar hyperplasia (CH). The main objective of this study was to develop approach determine normal activity values the mandibular condyles, adjusted age sex, through quantitative analysis bone single-photon emission computed tomography (SPECT) on a condyle-by-condyle basis compare these ...

UNLABELLED Hybrid cameras combining SPECT and spiral CT offer the opportunity to obtain a diagnostic-quality CT image of scintigraphically suggestive lesions that directly correlates with the SPECT image. The field of view of the CT scan can be adapted on the basis of the SPECT findings ("SPECT-guided CT"). The aim of the present study was to investigate the value of SPECT-guided CT in the asse...

Bone scan analyses and clinical assessment are used to diagnose unilateral condylar hyperactivity (UCH). This review compares the diagnostic accuracy of planar and SPECT bone scans. Studies diagnosing patients with possible UCH using bone scans, published between 1968 and 2008, were included in this review. Of 15 articles that met the inclusion criteria, 7 presented results in sufficient detail...