In assignment problems, decision makers are often interested in not only the optimal assignment, but also sensitivity of to perturbations weights. Typically, individual weights considered. We present a novel extension traditional analysis by allowing for simultaneous variations all Focusing on bottleneck problem, we provide two different methods quantifying and algorithms each. Numerical exampl...

The bottleneck governing infectious disease transmission describes the size of the pathogen population transferred from the donor to the recipient host. Accurate quantification of the bottleneck size is particularly important for rapidly evolving pathogens such as influenza virus, as narrow bottlenecks reduce the amount of transferred viral genetic diversity and, thus, may decrease the rate of ...