conclusions mild traumatic brain injuries despite of the normal ct scan and history of substance abuse are closely related to psychological symptoms. therefore, it is recommended that patients with brain trauma 6 months post-injury and subjects with a history of substance abuse be evaluated for psychological distress to support better rehabilitation. background it is well-known that severe brai...

background several lines of evidence suggest that early sensory stimulation and regular family visiting programs are potential nursing interventions to improve the outcomes of head injured comatose patients. however, little is known about the impacts of family involvement in providing sensory stimulation. objectives to determine the effects of a sensory stimulation program conducted by nurses a...

objective(s): neuroprotective effects of female gonadal steroids are mediated through several pathways involving multiple peptides and receptors after traumatic brain injury (tbi). two of these peptides are including the regulatory peptides neuromedin u (nmu) and neuromedin s (nms), and their common receptor neuromedin u2 receptor (nmur2). this study investigates the effects of physiological do...

introduction: brain injury is an important cause of morbidity and mortality worldwide and so far, there has been no absolute treatment for the damaged brain tissue. using human stem cells with self-assembling scaffolds can be a promising method for treatment of traumatic brain injury. materials and methods: human meningioma stem cells were isolated, cultured and then expanded into in vitro cond...

introduction: timely diagnosis and treatment of post traumatic, elevated intracranial pressure (eicp), could reduce morbidity and mortality, as well as improve patients’ outcome. this study is trying to evaluate the diagnostic accuracy of sonographic optic nerve sheath diameter (onsd) in detection of eicp. methods: sonographic onsd of patients with head trauma or cerebrovascular accident suspic...

Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality in young adults and children, and is a leading public health problem worldwide. In TBI, neurological impairment is caused by immediate brain tissue disruption (primary injury) and post‑injury cellular and molecular events (secondary injury) that exacerbate the primary neurological insult. However, the destructi...

this study briefly reviews the heart abnormalities in diverse intracranial pathologies, including strokes, spontaneous and traumatic subarachnoid hemorrhage and intracranial hemorrhage, and presents the results of a one-year prospective study of heart abnormalities in patients with moderate to severe head injuries and subarachnoid hemorrhage. different abnormalities such as: qt -interval, t -wa...

objective: to investigate the effects of intracranial pressure (icp) monitoring on mortality rate and functional outcome of patients with severe traumatic brain injury (tbi). methods: this was historical cohort study being performed in nemazee hospital of shiraz during a 4-year period (from 2006 to 2010) including those patients with severe tbi who had undergone care based on icp monitoring (ca...

background: cerebral vasospasm is a preventable cause of death and disability in patients who experience aneurysmal subarachnoid hemorrhage (sah). the aim of this study is to investigate the incidence of cerebral vasospasm following traumatic sah and its relationship with different brain injuries and severity of trauma. method s: this cross-sectional study was conducted from october 2006 to mar...

computed tomography (ct) is now the primary diagnostic method for head trauma because of its ability to demonstrate the nature, extent, sites, and multiplicity of brain injuries. although there have been numerous reports on the ct findings of most types of intracranial injury, the findings in brainstem injury have not been well described. this study aimed at comparing the autopsy findings of br...