PURPOSE The AccuBoost brachytherapy system applies HDR 192Ir beams peripherally to the breast using collimating applicators. The purpose of this study was to benchmark Monte Carlo simulations of the HDR 192Ir source, to dosimetrically characterize the round applicators using established Monte Carlo simulation and radiation measurement techniques and to gather data for clinical use. METHODS Do...

Image-guided surgery may reduce the re-excision rate in breast-conserving tumor-resection surgery, but image guidance is difficult since the breast undergoes significant deformation during the procedure. In addition, any imaging performed preoperatively is usually conducted in a very different presentation to that in surgery. Biomechanical models combined with low-cost ultrasound imaging and la...

PURPOSE In medical imaging systems, proper rendition of anatomy is essential in discerning normal tissue from disease. Currently, digital breast tomosynthesis (DBT) systems are evaluated using subjective evaluation of lesion visibility in uniform phantoms. This study involved the development of a new methodology to objectively measure the rendition of a 3D breast model by an anthropomorphic bre...

A simple and accurate measurement of breast density is crucial for the understanding of its impact in breast cancer risk models. The feasibility to quantify volumetric breast density with a photon-counting spectral mammography system has been investigated using both computer simulations and physical phantom studies. A computer simulation model involved polyenergetic spectra from a tungsten anod...

We propose a finite-element method (FEM) deformable breast model that does not require elastic breast data for nonrigid PET/MRI breast image registration. The model is applicable only if the stress conditions in the imaged breast are virtually the same in PET and MRI. Under these conditions, the observed intermodality displacements are solely due the imaging/reconstruction process. Similar stre...

It is shown that using elliptically polarized light permits selecting well-defined subsurface volumes in a turbid medium. This suggests the possibility of probing biological tissues at specific depths. First, we present the method and preliminary results obtained on an Intralipid phantom. We next report on the method's performance on a biological phantom (chicken breast) and, finally, on the ex...

Biomedical applications necessitate some restrictions on the type of devices to be used. When Ultra-Wide Band signals are used, the antenna is better to be directional and small in size. This paper presents a modified directional patch antenna design and fabrication which was used in real breast cancer detection experiments using breast phantom. It shows optimistic results.

Breast cancer is a global health problem, needing cheep and effective alternative diagnosis methods in order to minimize the mortality. This experimental study is performed in the context of an ongoing collaborative project towards a future planar three-dimensional microwave breast mammography system. Herein the first quantitative image of an inhomogeneous breast tumor phantom, composed by diff...

This work describes a technique which has been developed for the detection and imaging of breast cancer tumours. It describes how 3D images can be reconstructed from 2D scalar intensity patterns, or holograms. An outline of the background theory in described followed by experimental results on paraffin wax breast phantoms Results demonstrate that this technique is capable of determining the loc...

This paper presents both simulation and experimental study to detect and locate breast tumors along with their classification as malignant and/or benign in three dimensional (3D) breast model. The contrast between the dielectric properties of these two tumor types is the main key. These dielectric properties are mainly controlled by the water and blood content of tumors. For simulation, electro...