The nuclear lamins form a fibrous structure, the nuclear lamina, at the periphery of the nucleus. Recent results suggest that lamins are also present as foci or spots in the nucleoplasm at various times during interphase of the cell cycle (Goldman, A. E., R. D. Moir, M. Montag-Lowy, M. Stewart, and R. D. Goldman. 1992. J. Cell Biol. 104:725-732; Bridger, J. M., I. R. Kill, M. O'Farrell, and C. ...

Telemetry studies have provided unprecedented information about the activity, spatial ecology and energetics of free-swimming fishes (Lucas & Baras, 2000; Cooke et al., 2004). These studies, however, require tagging of fishes with radio or acoustic transmitters. The effects of these transmitters are often assumed to be negligible as far as the transmitter:fish mass ratio (Rtf) is <2% in air (Wi...

Research is a design activity whose decisions involve the ways in which research is carried out and its results interpret. These activities comprise what is referred to as research methodology. This paper brings the concepts of capturing design rationale and machine learning to bear on the design of research itself. Therefore, design decisions concerning research must be recorded to allow for u...

Abstract. Deep persistent slab avalanches are capable of destroying infrastructure and usually unsurvivable for those who caught. Formation a snowpack conducive to deep is typically driven by meteorological conditions occurring in the beginning weeks months winter season, yet avalanche event may not occur several later. While predicting exact timing release difficult, onset activity commonly pr...

Avalanche injury data has generally been derived from medical evaluation of victims, or in the worst case, by autopsy. These post-event examinations evaluate injuries sustained, but cannot directly determine the forces or impact loads experienced by the victim. If an individual is caught in a slide, what forces and accelerations are experienced, and what injuries might result? The MSU Avalanche...

The Whistler Squat Quarry (TMM 41372) of the lower Devil's Graveyard Formation in Trans-Pecos Texas is a middle Eocene fossil locality attributed to Uintan biochronological zone Ui1b. Specimens from the Whistler Squat Quarry were collected immediately above a volcanic tuff with prior K/Ar ages ranging from ∼47-50 Ma and below a tuff previously dated to ∼44 Ma. New 40Ar/39Ar analyses of both of ...

Let Λ be a quasi k-Gorenstein ring. For each dth syzygy module M in mod Λ (where 0 ≤ d ≤ k − 1), we obtain an exact sequence 0 → B → M ⊕ P → C → 0 in mod Λ with the properties that it is dual exact, P is projective, C is a (d + 1)st syzygy module, B is a dth syzygy of Ext Λ (D(M),Λ) and the right projective dimension of B ∗ is less than or equal to d − 1. We then give some applications of such ...

Adenosine 5’-0-(3-thio)triphosphate (ATPrS) has been shown to be a potent inhibitor of Escherichia coli succinyl-CoA synthetase. This inhibition was competitive with respect to ATP and GTP (Ki values of 0.8 and 0.7 PM, respectively) and mixed with respect to CoA and succinate. ATP-yS previously had been shown to be a weak substrate of the enzyme, probably because of the relatively sluggish rea...

Thorough characterization of probabilities detection (POD) and quantification uncertainties is fundamentally important to understand the place aerial measurement technologies in alternative means emission limitation (AMEL) or alternate fugitive emissions management programs (Alt-FEMP); monitoring, reporting, verification (MRV) efforts; surveys designed support measurement-based inventories miti...