Abstract Chronic renal failure is one of the leading causes death in African lions, cheetahs, and tigers. Conventional methods to measure dysfunction include measuring serum creatinine blood urea nitrogen (BUN). Symmetric dimethylarginine (SDMA) measurement a reliable predictor domestic cat because SDMA levels increase early when kidneys are damaged. Serum were assessed correlated with as well ...

Abstract To investigate the effect of pomegranate juice (PJ) on cyclosporine (CsA)-induced nephrotoxicity in rats, 80 rats were divided into four groups. The first group was regarded a negative control group, and others as follows: 2 (CsA group) received CsA dose 25 mg/kg/day orally, 3 (treated plus 2.5 mL/day PJ, 4 (PJ mL PJ daily. By end 21st day, plasma creatinine, blood urea nitrogen (BUN),...

Escherichia coli'den türetilen lipopolisakkarit (LPS), sepsis ve septik şok için bir model olarak yaygın kullanılmıştır. Çalışmamızda LPS ile deneysel endotoksemi oluşturulan ratlarda, marbofloksasin, diklofenak sodyum, metilprednizolon kullanılarak, bu ilaçların organ yetmezliğinin indirekt belirteçleri olan alkalen fosfotaz (ALP), alanin aminotransferaz (ALT), aspartat (AST), gama glutamil tr...

The effect of cystone, a polyherbal ayurvedic preparation, on the nephrotoxicity and antitumor activity of cisplatin is studied in C57BL/6J mice bearing B16F1 melanoma. Intraperitoneal administration of cisplatin 6 mg/kg, resulted in significant reduction of body weight, elevation of blood urea nitrogen (BUN) and serum creatinine levels on day 5. Cystone was found to protect tumor-bearing mice ...

The most frequent laboratory abnormalities in patients with congenital portosystemic shunts (CPSS) are microcytosis, hypoglycemia, hypoalbuminemia, hypoproteinemia, increased liver enzyme activities, decreased blood urea nitrogen (BUN) and urate crystalluria. The microcytosis is probably due to impaired iron transport. Hypoglycemia, hypoalbuminemia, hypoproteinemia and decreased BUN are partly ...

BACKGROUND Nephrotoxicity and hepatotoxicity are side effects of Cisplatin (CP) therapy. OBJECTIVES We investigated the role of gender in CP-induced nephrotoxicity and hepatotoxicity. MATERIALS AND METHODS Low dose of CP (1 mg/kg/day; ip) was administered daily to male and female Wistar rats for 15 consecutive days. Serum creatinine (Cr), blood urea nitrogen (BUN), malondialdehyde (MDA), ni...

BACKGROUND Although there are a few reports of recurrence of multiple myeloma in the transplanted kidney, recurrence of multiple myeloma (MM) presenting, as an isolated lesion in the brain, has been reported rarely. CASE REPORT Here we present a 60-year-old woman who underwent a kidney transplantation following a rise in her BUN and creatinine, having shown advanced tubulo-interstitial nephri...

Received for publication 8 February 1973 and in revised form 18 April 1973. measured with 3H20. Then MIRUS is calculated as: ([mg urea N excreted between 8 and 24 h after dose E] + [BUN at 24 h-BUN at 8 h] X [body water]) X (100/% recovery ["C]urea) X (1/kg BW314) X (1/ 16h). MRUS in 10 normal subjects averaged 65 mg urea N/h per kg BW"' (range 55-76), and in 34 cirrhotics 27 mg urea N/h per kg...