Objective(s): The aim of the present study was to evaluate the effect of Quercus brantii galls extract on the rat skin burn wound healing. Materials and Methods: Ethanol extract of the galls of Q. brantii was used to treat the induced burn wounds on the back of 32 Wistar rats divided into 4 groups. The groups were treated by placebo, 1%, 2% and 4% concentration gall extract gels for 14 days and...

INTRODUCTION Managing burn injury-associated pain and wounds is a major unresolved clinical problem. Opioids, nonsteroidal antiinflammatory drugs (NSAIDs), antidepressants and anticonvulsants remain the most common forms of analgesic therapy to treat burn patients. However, prolonged treatment with these drugs leads to dose escalation and serious side effects. Additionally, severe burn wounds c...

BACKGROUND Severe burns are a common and highly lethal trauma. The key step for severe burn therapy is to promote the wound healing as early as possible, and reports indicate that mesenchymal stem cell (MSC) therapy contributes to facilitate wound healing. In this study, we investigated effect of human umbilical cord MSCs (hUC-MSCs) could on wound healing in a rat model of severe burn and its p...

Background Burn is still a majordevastating condition in emergency medicine departments among both genders and all age groups in all developed and developing countries, leading to physical, psychological scars and economical burden. The present study aimed to determine the healing effect of topical treatment with Arnebia euchroma on second-degree burn wound in rats. Methods Fifty rats were ...

Background: Efficacy of Centella asiatica on incision and burn wounds are not sufficiently known. In this study we evaluated[SYG1] wound healing activities of different extracts of Centella asiatica, namely hexane, ethyl acetate, methanol, and water extracts, in incision and partial-thickness burn wound models in rats. Results: On day 7 post-wounding, tensile strength of incision wound in all e...

background burn is still a majordevastating condition in emergency medicine departments among both genders and all age groups in all developed and developing countries, leading to physical, psychological scars and economical burden. the present study aimed to determine the healing effect of topical treatment with arnebia euchroma on second-degree burn wound in rats. methods fifty rats were divi...

INTRODUCTION Conventional management of partial thickness facial burn wounds includes the use of silver sulphadiazine dressings. Silver sulphadiazine forms an overlying slough that makes wound healing assessment difficult. Moist exposed burn ointment (MEBO) has been proposed as the ideal burn wound dressing both for burns of the face and other sites. Proponents of MEBO claim that it accelerates...

Following severe burn injury, persistent inflammation perpetuated by surface eschar, bacterial colonisation and neutrophil proteolytic activity can impede normal healing and result in further tissue damage. Extracorporeal shock wave treatment (ESWT) has been shown in the clinical setting to promote the healing of burn and difficult-to-heal wounds; however, the mechanism is unclear. We investiga...

The ultimate goal in the management of burn wounds is to obtain physiological closure in the shortest period of time. Traditional burn wound management involves cleansing, debridement and provision of a moist environment to encourage the process of natural healing. Hence, an ideal dressing material has to maintain a moist environment, act as a bacterial barrier, and as a medium for free exchang...