background & objectives: neutrophils are the most important member of granulocytes & the first line of host defence against micro-organisms. they kill micro-organisms entering the body by phagocytic activity. one of the important phases of phagocytic activity is respiratory burst which can be effected by different drugs such as cimetidine. in this study the effects of cimetidine on respiratory ...

Incubation of hippocampal slices in zero-Ca(2+) medium blocks synaptic transmission and results in spontaneous burst discharges. This seizure-like activity is characterized by negative shifts (bursts) in the extracellular field potential and a K(+) wave that propagates across the hippocampus. To isolate factors related to seizure initiation, propagation, and termination, a number of pharmacolog...

Theta-burst transcranial magnetic stimulation could modulate cortical excitability and has the potential to treat refractory depression. However, there has been a lack of large randomized studies of the antidepressant efficacy of different forms of theta-burst stimulation, such as intermittent and continuous theta-burst stimulation. A randomized sham-controlled study was conducted to investigat...

Previous experiments have shown that individual bacteriophage infections of Escherichia coli cells have burst sizes ranging from a few phage to hundreds of phage. It was proposed that larger cells have more cellular machinery and can therefore support higher rates of phage production resulting in larger burst sizes. The effect of cell size on the ability of T4 bacteriophage to replicate and lys...

Minimum audible angles (MAAs) were estimated for single noise bursts, and for burst pairs that satisfied the conditions of the precedence effect (that is, produced fused images). In one burst-pair condition, the bursts to be discriminated differed in lead location; in the other, they differed in lag location. Sounds were presented over loudspeakers. MAAs were lowest for single bursts, slightly ...

Epilepsy is a common disease of the central nervous system. Tetanic spasms and convulsions are the key symptoms exhibited during epileptic seizures. However, the majority of patients have a significant post‑seizure silence following a serious seizure; the underlying molecular neural mechanisms in this burst interval are unclear. The aim of the present study was to reveal the effect and role of ...

objective: electroporation can be a highly efficient method for introducing the foreign genetic materials into the targeted cells for transient and/or permanent genetic modification. considering the application of this technique as a very efficient method for drug, oligonucleotide, antibody and plasmid delivery for clinical applications and production of transgenic animals, the present study ai...

This paper presents a new analytical model for calculating burst loss rate (BLR) in a slotted optical burst switched network. The analytical result leads to a framework which provides guidelines for optical burst switched networks. Wavelength converter is used for burst contention resolution. The effect of several design parameters such as burst arrival probability, wavelength conversion capabi...

Recently we found that certain antibiotics which are markedly concentrated by human polymorphonuclear leukocytes (PMN) failed to kill susceptible, intraphagocytic Staphylococcus aureus, even though cellular drug levels were quite high. The possibility that specific antibiotics might adversely affect phagocyte antibacterial function was considered. Thus, we studied the effects of multiple antibi...

Rock burst is the most attractive and hot research area in geomechanics, mining, and civil engineering due to the increasing depth of mines and construction of deep underground structures. It has also been a severe problem in ground control measures in the last few decades. Many studies have been done by different researchers in order to minimize the hazards of rock burst and to provide a safe ...