The molecular mechanisms involved in the hepatic tropism of hepatitis C virus (HCV) have not been identified. We have shown previously that liver-expressed C-type lectins L-SIGN and DC-SIGN bind the HCV E2 glycoprotein with high affinity (Lozach, P. Y., Lortat-Jacob, H., de Lacroix de Lavalette, A., Staropoli, I., Foung, S., Amara, A., Houles, C., Fieschi, F., Schwartz, O., Virelizier, J. L., A...

Cytochrome-c (cyt-c) is an electron transport protein, and it is present throughout the evolution. More than 280 sequences have been reported in the protein sequence database (www.uniprot.org). Though sequentially diverse, cyt-c has essentially retained its tertiary structure or fold. Thus a vast data set of varied sequences with retention of similar structure and fun...

For two types of moderate growth representations $(\mathbb{R}^d,+)$ on sequentially complete locally convex Hausdorff spaces (including F-representations [J. Funct. Anal. 262 (2012), 667-681], we introduce Denjoy-Carleman classes ultradifferentiable vectors and show a strong factorization theorem Dixmier-Malliavin type for them. In particular, our solves [Conjecture 6.; J. 667-681] analytic $G ...

It is well known that fluorescent traffic sign have a daytime conspicuity that is far superior to that of normal color signs. This study was conducted in order to test the hypothesis if adding the property of fluorescence while leaving all (or in practical terms most) other sign features the same, does in fact increase the legibility distance. Six diamond shaped signs were fabricated and lamina...

We consider the problem of deciding the best action time when observations are made sequentially. Specifically we address a special type of optimal stopping problem where observations are made from state-contingent distributions and there exists uncertainty on the state. In this paper, the decision-maker's belief on state is revised sequentially based on the previous observations. By using the ...

We show that the classical strong maximum principle, concerning positive supersolutions of linear elliptic equations vanishing on boundary domain $ \Omega can be extended, under suitable conditions, to case in which forcing term f(x) is changing sign. In addition, for solutions normal derivative may also vanish (definition flat solutions). This leads examples unique continuation property fails....

Recent advances in visual recognition show overarching success by virtue of large amounts of supervised data. However, the acquisition of a large supervised dataset is often challenging. This is also true for intelligent transportation applications, i.e., traffic sign recognition. For example, a model trained with data of one country may not be easily generalized to another country without much...

It is shown that there always exists a coordinate system in which components of property tensors that distinguish between the domains of a magnetic non-ferroelastic domain pair differ solely in the two domains by a change in sign. The 309 classes of twin laws of magnetic non-ferroelastic domain pairs are listed and the twin laws, which are given in a coordinate system where the tensor distincti...

We prove the first stability estimates for the ENO reconstruction procedure. They take the form of a sign property: we show that the jump in the reconstructed pointvalues at each cell interface has the same sign as the jump in underlying cell averages (cell centered values) across the interface. Moreover their ratio is upper bounded. These estimates hold for arbitrary orders of accuracy of the ...