Surfactant predominantly comprises phosphatidylcholine (PC) species, together with phosphatidylglycerols, phosphatidylinositols, neutral lipids, and surfactant proteins-A to -D. Together, dipalmitoyl-PC (PC16:0/16:0), palmitoyl-myristoyl-PC (PC16:0/14:0), and palmitoyl-palmitoleoyl-PC (PC16:0/16:1) make up 75-80% of mammalian surfactant PC, the proportions of which vary during development and i...

OBJECTIVES To compare the sensitivity and specificity of C[14] urea breath test with histopathological findings in biopsies obtained through endoscopy. METHODS In this cross-sectional study, conducted at the Medical Faculty Ankara University, Ankara, Turkey between January and October 2009, 100 patients aged 65 and above who fulfilled the criteria for inclusion were enrolled. Oesophago-gastro...

Some investigators tried to rebut the C14 dating by pointing out the problems with this method. All biological materials do not absorb C14 at the same rate and there was no absolute proof that the amount of C14 in the atmosphere had remained invariant before the industrial revolution. Ogden (1) pointed out these discrepancies in 1977, but since that time calibration methods have been developed ...

Kelly and associates (8, 10, 20) have demon strated that phosphorus-32 is incorporated to a greater extent into the liver, kidney, and spleen deoxyribonucleic acid in mice bearing mammary carcinomas than into those of normal control mice. Comparable results were also obtained by those investigators (19) when tumor-bearing mice were given injections of either formate-carbon-14 (C14) or glycine-2...

OBJECTIVE The role of mitochondrial function in the complex pathogenesis of type 2 diabetes is not yet completely understood. Therefore, the aim of this study was to investigate serum concentrations of short-, medium- and long-chain acylcarnitines as markers of mitochondrial function in volunteers with normal, impaired or diabetic glucose control. METHODS Based on a 75 g oral glucose toleranc...

Although considerable research has been conducted in recent years on the mechanisms of fatty acid synthesis and oxidation in animal tissues (1) and in microorganisms (2), no similar studies of higher plants have yet been reported, despite the great importance of fat-storing seeds and fruits in the economy of nature and the value to comparative biochemistry of an understanding of fatty acid biog...

The microstructures of two metal hydride (MH) alloys, a Zr7Ni10 based Ti15Zr26Ni59 and a C14 Laves phase based Ti12Zr21.5V10Ni36.2Cr4.5Mn13.6Sn0.3Co2.0Al0.4, were studied using the electron backscatter diffraction (EBSD) technique. The first alloy was found to be composed of completely aligned Zr7Ni10 grains with a ZrO2 secondary phase randomly scattered throughout and a C15 secondary phase pre...

AIM Cationic ethylphosphatidylcholines (ePCs) were evaluated for the delivery of siRNA in modified breast cancer cells. MATERIALS AND METHODS Dimyristoleoyl-ePC (C14), dioleoyl-ePC (C18), and dilauroyl-ePC (C12) nanoparticles were complexed with siRNA for green fluorescent protein (GFP) suppression in modified MCF-7 breast cancer cells. The kinetics of GFP suppression were followed over the c...

Weinhouse and co-workers (39-43) have estab lished that the Krebs tricarboxylic acid cycle operates in a variety of experimental tumors and that fatty acid oxidation, believed to be non existent in tumors (9), provides 2-carbon frag ments for continuous operation of this cycle in neoplastic tissues. Our studies with the mouse hepatoma C954, carried by mice of the C57-Leaden strain, also led us ...