Objective: To evaluate the clinical significance of serum levels of Tartrate Resistant Acid Phosphatase 5b (TRACP5b), Carcino-Embryonic Antigen (CEA) and CA-153 in predicting the bone metastasis in patients diagnosed with lymph node-negative breast cancer. Methods: Seventy-seven patients pathologically diagnosed with lymph node-negative breast cancer were recruited in the breast cancer group an...

A two-dimensional resolution system of channels and substrate zones was proposed for multiplex immunoassay performed with a designed multichannel chemiluminescent (CL) detection device coupled with a single photomultiplier. Using carcinoma antigen 125 (CA 125), carcinoma antigen 153 (CA 153), carcinoma antigen 199 (CA 199), and carcinoembryonic antigen (CEA) as two couples of model analytes, tw...

Calsenilin/DREAM/KChIP3, a neuronal Ca(2+)-binding protein, has multifunctions in nucleus and cytosol. Here, we identified CLN3 as a calsenilin-binding partner whose mutation or deletion is observed in Batten disease. In vitro binding and immunoprecipitation assays show that calsenilin interacts with the C-terminal region of CLN3 and the increase of Ca(2+) concentration in vitro and in cells ca...

Inclusive and coincidence measurements have been performed to study symmetric products from the reactions 74—186 MeV ' C+ Ca, 141 MeV Be+ Ca, and 153 MeV Li+ Ca. The binary decay of the composite system has been verified. Energy spectra, angular distributions, and fragment correlations are presented. The total kinetic energies for the symmetric products from these very light composite systems a...

Y. LI*{, P. GONG{§ and T. SASAGAWA" {International Institute for Earth System Science, Nanjing University, Nanjing, Jiangsu, 210093, PRC {Institute of Remote Sensing Applications, Chinese Academy of Sciences, 100101, Beijing, PRC §Center for Assessment and Monitoring of Forest and Environmental Resources (CAMFER), UC Berkeley, 151 Hilgard Hall, Berkeley, CA, 94720-3110, USA "PASCO Corporation, ...

Pursuit of superconductivity in light-element systems at ambient pressure is great experimental and theoretical interest. In this work, we combine a machine learning (ML) method with first-principles calculations to efficiently search for the energetically favorable ternary Ca-B-C compounds. Three layered borocarbides (stable $\mathrm{CaB}{\mathrm{C}}_{5}$ metastable ${\mathrm{Ca}}_{2}\mathrm{B...