Introduction Hydroxyl ion release from calcium hydroxide is responsible for the key attributes of broad spectrum antimicrobial activity, penetration into biofilms, inhibition of endotoxins, and dissolution of organic tissues.1,2 The maximum solubility of calcium hydroxide in water at 25C is only 0.159 g/100mL (0.16%), and this reduces to 0.140 g/100 mL (0.14%) at 40C, with an accompanying decre...

AIM To investigate the chemical interaction of calcium hydroxide with the antibiotics demeclocycline calcium in Ledermix Paste and clindamycin hydrochloride in Odontopaste. METHODOLOGY Validated methods were developed to analyse the interaction of calcium hydroxide in two forms, Pulpdent and calcium hydroxide powder, with the two antibiotics. High-performance liquid chromatography (HPLC) was ...

The purpose of this investigation was to examine the in vitro susceptibility of Candida albicans to a mixture of chlorhexidine and calcium hydroxide using a tube dilution test. A suspension containing C. albicans was exposed to 2% chlorhexidine solution, calcium hydroxide paste and 2% chlorhexidine mixed with calcium hydroxide in plastic tissue culture wells. The tested agents were incubated wi...

The purpose of endodontic therapy is to preserve the patient's natural teeth without compromising the patient's local or systemic health. Calcium hydroxide has been included in several materials and antimicrobial formulations that are used in several treatment modalities in endodontics, such as inter-appointment intracanal medicaments. The purpose of this article was to review the antimicrobial...

microorganisms play a major role in the initiation and perpetuation of pulpal and periapical disease. in order to predictably achieve a bacteria-free root canal system, it is necessary to use intracanal medicaments. calcium hydroxide is the most common intracanal medicaments. it is effective against primary infections. however, its effectiveness against enterococcus faecalis and candida albican...

introduction: one of the major contributing factors, which may cause failure of endodontic treatment, is the presence of residual microorganisms in the root canal system. for years, most dentists have been using calcium hydroxide (ch) as the intracanal medicament between treatment sessions to eliminate remnant microorganisms. reducing the size of ch particles into nanoparticles enhances the pen...

objective: bioactive glass is often used as a filler material for repair of dental bone defects. in different studies osteogenic potential of this material was proved, but its dentinogenesis property is in doubt. the purpose of this study was to evaluate the histological pulp responses of calcium hydroxide and bioactive glass placed directly on exposed pulp tissues. materials and methods: twent...

nanocrystalline hydroxyapatite was precipitated from calcium hydroxide and phosphoric acid. effects of precipitation temperature and different calcium to phosphate ratios (ca/p) on the obtained powders were investigated. characteriza-tion of the powders was performed using xrd and ftir spectra, scanning electron microscopy, and transmission electron microscopy. increase in precipitation tempera...

introduction: an ideal intracanal medicament should be able to eliminate any remaining intracanal microorganism. the aim of this study was to compare the antimicrobial effects of bioglass 45s5 with calcium hydroxide on enterococcus ( e ) faecalis in-vitro . materials & methods: direct exposure test (det) was used to evaluate the antimicrobial effect of bioglass 45s5, calcium hydroxide and norma...

introduction: some studies in dental literature have proposed that short term and long term exposure of root dentin to calcium hydroxide predisposes it to fracture. mineral trioxide aggregate (mta) and a recently introduced endodontic material, calcium-enriched mixture (cem) cement may be used instead of calcium hydroxide and might have an effect on the strength of root dentin. therefore, the a...