Calendula officinalis Linn (Asteraceae), is an aromatic annual herb, which is used in Traditional System of Medicine to treat various diseases like anti-inflammatory, antitumour, antispasmodic. The reported constituents are flavonoids, glycosides and saponins. From literature it was found that the quantification work was not carried out. It is considered to contain Quercetin, confirmed by TLC a...

Lipopolysaccharide-induced nitric oxide and the protease prolyl oligopeptidase (EC 3.4.21.26) have been proposed as targets for the treatment of cognitive disturbances such as dementia. In this study, nine triterpenoids isolated from the roots of Sanguisorba officinalis, including arjunic acid (1), rosamultic acid (2), haptadienic acid (3), 1β-hydroxyeuscaphic acid (4), euscaphic acid (5), torm...

The present study was carried out to investigate biochemical responses of marigold (Calendula officinalis L.) to Bio-organic fertilizers. Effects of co-inoculation of two plant growth-promoting rhizobacteria (PGPR) (Azotobacter sp.145PI and Azospirillum sp.AC49I), humic acid (HA) (10 kg ha−1), vermicompost (VC) (7 T ha−1) and combinations of these treatments were evaluated in two marigold culti...

PURPOSE Aldose reductase (AR) has been a drug target because of its involvement in the development of secondary complications of diabetes including cataract. Although numerous synthetic AR inhibitors (ARI) have been tested and shown to inhibit the enzyme, clinically synthetic ARIs have not been very successful. Therefore, evaluating natural sources for ARI potential may lead to the development ...

INTRODUCTION Diaper dermatitis (DD) is a common inflammatory disorder among children and infants. The objective of the present randomized and double-blind trial was to compare the therapeutic efficacies of aloe vera cream and Calendula officinalis ointment on the frequency and severity of DD in children. METHODS Sixty-six infants with DD (aged < 3 years) were randomized to receive either aloe...

BACKGROUND The use of medicinal plants is an option for livestock farmers who are not allowed to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock. METHODS In 2003 we conducted semi-structured interviews with 60 participants obtained using a purposive sample. Medicinal plants are used to treat a range of condi...

The aim of this study was to evaluate the safety, tolerability and pharmacokinetics of single dose of Melissa officinalis extract which contained rosmarinic acid, including food-effects in healthy individuals. A total of eleven healthy individuals were randomly assigned to treatment arms in the two studies [Study 1 (fasted state) and Study 2 (fed state)]. Rosmarinic acid in serum was measured b...