Background: Calotropis gigantea of family Asclepiadaceae, is traditionally used in ayurveda for its anti-helminthic, anti-pyretic, and anti-malarial activities. The present study was designed to investigate the sub-acute toxic effects of ethanol and methanol extract of Calotropis gigantea latex in mouse model using haematology, serum biochemistry and histopathological changes as toxicity indice...

Apocynaceae is a large family of tropical trees, shrubs and vines with most species producing white latex. Major metabolites of species are triterpenoids, iridoids, alkaloids and cardenolides, which are known for a wide range of biological and pharmacological activities such as cardioprotective, hepatoprotective, neuroprotective, anti-inflammatory, anticancer and antimalarial properties. Prompt...

calotropis procera is a small, erect plant, which is used in several traditional medicines to treat many diseases. it is a native of most of the asian and african countries. all plant parts exude thick white milky juice (latex) on cut or break. this shrub has been known to possess analgesic, antitumor, antihelmintic, antioxidant, hepatoprotective, antidiarrhoeal, anticonvulsant, antimicrobial, ...

Different parts of Acacia nilotica (L.) Delile, Calotropis procera (Aiton) W.T. Aiton, Adhatoda vasica Nees, Fagoniaar abica L. and Casuarina equisetifolia L. are traditionally used in folk medicine for the treatment of a variety of common ailments like nausea, cold, cough, asthma, fevers, diarrhea, sore throat, swelling, etc. The present study was aimed to evaluate the anti-Helicobacter pylori...

Calotropis Procera (CP) has been used in the management of toothache, fresh skin burns, gum bleeding as well as others to make it qualify as a medicinal plant. This study was designed to assess its wound-healing property in rabbits and its potentials for anti keloidal activity.Fresh latex of Calotropis were obtained and evaluated phytochemically. Fifteen male rabbits were used and four excision...

Calotropis procera is a medicinal plant whose pharmacological properties are associated with its latex. Here, the Calotropis procera latex fractions were investigated in an attempt to trace its phytochemical profile and measure its anti-inflammatory and toxicity activity. The crude latex was partitioned, yielding five fractions (49.4% hexane, 5.2% dichloromethane, 2.0% ethyl acetate, 2.1% n-but...

The present study deals with the cytotoxic activity of cardiac glycosides of Calotropis gigantea (L.) W.T.Aiton; on breast cancer cell line MCF-7. Qualitative screening of methenaloic extract of leaves of Calotropis gigantea for secondary metabolites showed the presence of phenolics, alkaloids, coumarins, saponins, tannins and glycosides. Glycosides were selected for detailed chemical analysis,...

BACKGROUND Over 60% of currently used anti-cancer agents are derived in one-way or another from natural sources, including plants, marine organisms and microorganisms. Calotropis gigantea (Linn.) (Family: Asclepiadaceae) is a perennial shrub and it is used as a traditional folk medicine for the treatment of various health complications. But there is no report on isolation of anticancerous chemi...

BACKGROUND & OBJECTIVES Identification of novel effective larvicide from natural resources is essential to combat developing resistances, environmental concerns, residue problems and high cost of synthetic insecticides. Results of earlier laboratory findings have shown that Calotropis procera extracts showed larvicidal, ovicidal and refractory properties towards ovipositioning of dengue vectors...