the aim of this study was to isolate mouse embryonic stem cells from late blastocyst stage embryos and to use them as a model system for the study of hematopoietic induction outside the embryo by coculturing of embryonic stem cells with bone marrow stromal cells. blastocyst stage embryos from pregnant nmri mice were obtained and cultured for 1-2 days in dmem medium. the inner cell masses formed...

Mesenchymal Stem Cells Trigger Epithelial to Transition in the HT-29 Colorectal Cancer Cell Line

stem cells from human exfoliated deciduous teeth (shed) have been introduced recently and  possess characteristics similar to  mesenchymal stem  cells (mscs). because of  their convenient accessibility and safety of harvest, shed can be a preferable source for the ever- increasing mscs’ applications. while they are new, their immunoproperties have not been adequately studied. in this study, we ...

Background and Aim: Cancer stem cells (CSCs) have been proposed as a driving force of tumor initiation, dissemination drug resistance. The protease inhibitor SerpinB3 (SB3) has involved in the early events hepatocarcinogenesis, is highly expressed hepatic progenitor cells. However, only limited information on possible role SB3 cholangiocarcinoma (CCA) stem-like compartment available.

Cancer stem cells (CSCs) are now well-established as key players in tumor initiation, progression, and therapy resistance [...]

Spinal cord injury (SCI) is a debilitating disease which leads to progressive functional damages. Because of limited axonal regeneration in the central nervous system, there is no or little recovery expected in the patients. Different cellular and molecular approaches were investigated in SCI animal models. Cellular transplantation of stem cells can potentially replace damaged tissue and provid...

background: despite the extensive information available in the literature, cell surface marker signature of human amniotic epithelial cells (haecs) remains controversial. the aim of the present study was to characterize immuno-phenotypic features, proliferative capacity and immunogenicity of haecs. we also tested whether expression of some cell surface markers is influenced by the type of tryps...

Mol. Nutr. Food Res. 2022, 66, 202200234 DOI: 10.1002/mnfr.202200234 Black raspberries (BRBs) play a role in colorectal cancer chemoprevention. The number of intestinal stem cells, the cells origin cancer, are reduced following BRB diet. This decreases chance mutation occurring within these and subsequently reduces risk developing cancer. is reported by Stephanie May, Lee Parry, co-workers arti...