Pharmaceutical compounds have been found in rivers and treated wastewaters. They often contaminate irrigation waters consequently accumulate edible vegetables, causing changes plants metabolism. The main objective of this work is to understand how lettuce cope with the contamination from three selected pharmaceuticals using a label free proteomic analysis. A hydroponic culture, grown for 36 day...

We describe an analytical method for determining carbamazepine in serum by electron-capture gas chromatography. A single-step extraction is followed by formation of the N-pentafluorobenzamide derivative with pentafluorobenzoyl chloride. For quantitation either of two internal standards may be used: 10-methoxy carbamazepine or 7-chloro-5,11-dihydrodibenz[b,e] [1,4]-oxazepine-5-carboxamide (Squib...

During an eight year period, 32 patients with definite or suspected multiple sclerosis (MS) were seen with paroxysmal neurological disturbances, which included tonic seizures, paroxysmal dysarthria, paraesthesiae and pain in the limbs, as well as trigeminal neuralgia. In 21 of these patients the paroxysmal disorders were treated with carbamazepine, and in six the effect was compared with placeb...

Epilepsy is a chronic cerebral disorder associated with recurrently occurring seizures resulting from over activity of brain neurons. Since more than one percent of the world's population is suffering from epilepsy, this disease is recognized as one of the most important neurological disorders in modern medicine. Studies indicate that impairment in balance and motor activity are known as one of...