Regular physical activity may play a protective role against cardiovascular disease in adults, and paraoxonase activity may serve to mediate this effect. This study compared paraoxonase activity and that of other antioxidative agents in adolescent athletes compared with inactive youth. Paraoxonase level was 177.32 +/- 100.10 (U/L) in children with regular physical activity and 98.11 +/- 40.92 (...

Uncontrolled cell growth and resistance to apoptosis characterize cancer cells. These two main features are initiated in cancer cells through mutations in key signaling molecules, which regulate pathways that are directly involved in controlling cell proliferation and apoptosis. Resveratrol (RSV), a naturally occurring plant polyphenol, has been shown to have biological effects counteracting di...

Curcumin, is a polyphenol from Curcuma longa (turmeric plant), is a polyphenol that belongs to the ginger family which has long been used in Ayurveda medicines to treat various diseases such as asthma, anorexia, coughing, hepatic diseases, diabetes, heart diseases, wound healing and Alzheimer's. Various studies have shown that curcumin has anti-infectious, anti-inflammatory, anti-oxidant, hepat...

Short-chain fatty acids (SCFAs) are microbial metabolites, mainly generated by the action of gut microbiota on dietary fibers. Acetate, propionate, and butyrate three main SCFAs produced typically in a 60:20:20 molar ratio colon. butyrate, when given individually as supplements, have shown protective role obesity hyperglycemia; however, sex-specific effects mixture SCFAs, ratio, regulation lipi...

Volatile anesthetic-induced preconditioning (APC) has shown to have cardiac and cerebral protective properties in both pre-clinical models and clinical trials. Interestingly, accumulating evidences demonstrate that, except from some specific characters, the underlying molecular mechanisms of APC-induced protective effects in myocytes and neurons are very similar; they share several major intrac...

The beneficial effects of nut consumption on cardiovascular disease (CVD) have been widely documented. These protective effects are mainly attributed to the role of nuts in the metabolism of lipids and lipoproteins. As chronic inflammation is a key early stage in the atherosclerotic process that predicts future CVD events and is closely related to the pathogenesis of insulin resistance, many re...

This article presents the nutritional value of shrimp on the strength of its nutrient composition and daily value (DV%). With its relatively lower lipid content (~ 1%), the DV (%) of 100 g shrimp for an adult human is 75%, 70% and 35% for eicosapentanoic acid + docosahexanoic acid, essential amino acids (methionine, tryptophan and lysine) and protein respectively. The lower atherogenic (0.36) a...

Obesity is a major risk factor for cardiovascular disease and its complications. However, not all fat depots share the same characteristics. Recent studies have found that ectopic rather than subcutaneous fat accumulation is associated with increased cardiometabolic risk. However, ectopic fat accumulation can be seen initially as a protective mechanism against lipotoxicity. Subsequently the adi...

Microvascular damage is frequently observed in the setting of acute coronary syndromes (ACS). Imaging of the microcirculation is playing an increasingly important role in the risk stratification of patients presenting with acute coronary syndromes, furthering our understanding about coronary microcirculatory patho-physiology in this setting. Of the available imaging methods, cardiac magnetic re...