Cardiovascular disease morbidity/mortality are increasing due to an aging population and the rising prevalence of diabetes obesity. Therefore, innovative cardioprotective measures required reduce cardiovascular morbidity/mortality. The role necroptosis in myocardial ischemia–reperfusion injury (MI–RI) is beyond doubt, but molecular mechanisms remain incompletely elucidated. Growing evidence sug...

Context: Cardiovascular disorders are a leading cause of mortality and morbidity worldwide, especially in people with diabetes. Due to synthetic drugs’ adverse effects, new medicines needed. Evidence Acquisition: Iranian traditional medicine (ITM) is one the oldest medical systems. In this article, we first introduce list cardiotonic medicinal plants based on ITM. Then review cardio-related eff...

Cardiovascular diseases involve abnormalities of the heart and blood vessels, such as coronary disease, hypertension, cerebrovascular are main cause increase in mortality rate world. Herbal plants tend to be very useful prevent cardiovascular disease. The phytoconstituents herbal medicinal like tannins, alkaloids, saponins, flavonoids, glycosides that have ability diseases. Examples Nerium olea...

Chocolate is a widely appreciated foodstuff with historical appreciation as food from the gods. In addition to its highly palatable taste, it rich source of (poly)phenolics, which have several proposed salutogenic effects, including neuroprotective anti-inflammatory, anti-oxidant and cardioprotective capabilities. Despite known benefits this ancient foodstuff, there paucity information on effec...

The cardioprotective effects of resveratrol are well established in animal models of metabolic disease but are yet to be investigated in a combined model of hypertension and diabetes. This study investigated the ability of resveratrol's antioxidant and anti-inflammatory effects to prevent cardiovascular complications in the spontaneously hypertensive streptozotocin-induced diabetic rat. Diabete...

Background: Due to this belief that opium may have beneficial effects on diabetes or cardiovascular risk factors, the present study aimed to assess the potential and possible effects of opium consumption on diabetes control and some cardiovascular risk factors in diabetic patients. Methods: This study enrolled 374 diabetic subjects from diabetes care centers in Kerman, Iran including opium user...

PURPOSE OF REVIEW This review evaluates clinical and experimental articles that have recently been published on the cardioprotective effect of perioperative statin therapy. RECENT FINDINGS Perioperative statin therapy improves short and long-term cardiac outcome following noncardiac surgery. This cardiovascular protection has been attributed to the so-called pleiotropic effects, which have a ...

Methotrexate is a disease-modifying antirheumatic drug commonly used to treat inflammatory conditions such as rheumatoid arthritis which itself is linked to increased cardiovascular risk. Treatments that target inflammation may also impact the cardiovascular system. While methotrexate improves cardiovascular risk, inhibition of the cyclooxygenase (COX)-2 enzyme promotes atherosclerosis. These o...

Hormone replacement therapy (HRT) was initially given to protect women against osteoporosis and alleviate menopausal symptoms, such as hot flashes, depression, sleep disturbances, and vaginal dryness. In view of the understanding of oestrogen deficiency as a major trigger for the acceleration of cardiovascular risk after menopause, HRT may also be proposed as a substantial beneficial cardioprot...

Advances in breast cancer treatment have improved disease-free survival and overall survival in women with early-stage breast cancer. However, these improvements may be attenuated by the adverse cardiovascular effects associated with breast cancer adjuvant therapy. Exercise may be a potential strategy to counteract these toxicities. The purpose of this paper is to provide an overview on the adv...