........................................................................................................................................... i Chapter 1: Introduction ................................................................................................................... 1 Cannabinoid Discovery and Background ...............................................................................

Inflammatory disorders alone or as a consequence of neurological disease affecting patients in life. Experimental models of inflammation are use to evaluate the production of inflammatory mediators at site of inflammation. Curcumin is one of the flavonoids possesses potent anti-inflammatory activity. However, because of low water solubility curcumin, its clinical application has been limited. T...

This article presents the complementary data regarding compatibilization of chitosan/κ-carrageenan polyelectrolyte complex for synthesizing of a soft film using ascorbic acid. It includes the thermal-theory for estimating the degradation of κ-carrageenan, as reflected in alteration of the structural properties of the blend. The data has been provided to demonstrate that the blend solution based...

BACKGROUND Paw carrageenan induces activation of phosphatidylinositol 3-kinase (PI-3K) and Akt in dorsal horn neurons in addition to induction of pain behavior. Spinal PI-3K activation is also thought to be required for inflammation-induced trafficking of GluA1, AMPA receptor subunits, into plasma membranes from cytosol. Phosphorylation of Akt has a unique time course. It occurs first in the su...

BACKGROUND The common cold is the most widespread viral infection in humans. Iota-carrageenan has previously shown antiviral effectiveness against cold viruses in clinical trials. This study investigated the efficacy of a carrageenan-containing nasal spray on the duration of the common cold and nasal fluid viral load in adult patients. METHODS In a randomized, double-blind, placebo-controlled...

Biopolymers such as carrageenan or collagen can be used carriers for loading a drug to enhance drug’s bioavailability. In this work, allopurinol was loaded on carrageenan/collagen blend and the carrageenan/collagen/allopurinol (CCA) biocomposite films were prepared using ionic gelation method combined with 3D printing gel ink material. The advantages of are ease in shaping design controlling th...

The aim of this study is to highlight novel CuS-carrageenan nanocomposites grown from the interface between sulfide solutions (liquid phases) and Cu-?-carrageenan gels. Several parameters including pH, copper carrageenan concentration hydrogel that influence growth nanocomposite have been examined. most effective parameter initial pH liquid phase, hence, three growing samples at 7, 10 13 were s...

Carrageenan is a natural carbohydrate (polysaccharide) obtained from edible red seaweeds. The name Carrageenan is derived from the Chondrus crispus species of seaweed known as Carrageen Moss or Irish Moss in England, and Carraigin in Ireland. Carraigin has been used in Ireland since 400 AD as a gelatin and as a home remedy to cure coughs and colds. It grows along the coasts of North America and...

Kappaphycus alvarezii is a marine alga cultivated in Indonesia and produces carrageenan. Carrageenan product used the cosmetic, food, pharmaceutical industries. This study aimed to test viscosity gel strength of refined carrageenan with addition natural dye phycoerythrin from algae Halymenia durvillei different concentrations. Refine was made using alkaline solvents 4% NaOH 5% KOH then boiled p...

background and objectives: otostegia persica (labiatae) is an endemic plant of iran and is used for its anti-inflammatory properties in folk medicine of sistan and baluchestan province. the aim of the present study was to investigate the anti-nociceptive and anti-inflammatory effects of o. persica different fractions and identification of the natural compounds from the most active fraction. met...