OBJECTIVES With regard to pharmacological effects of carvacrol on the respiratory system, its effect on cytokines genes expression in splenocytes of asthmatic mice was examined in this study. MATERIALS AND METHODS Splenocytes were isolated from non-sensitized (control group), sensitized mice to ovalbumin (OVA) (group S), and S animals treated with dexamethasone, and three concentrations of ca...

background and objective: a huge amount of investigational evidence support a role for oxidative stress as an intermediary of nerve cell dysfunction in parkinson’s disease (pd). polyphenols such as carvacrol have been indicated to prevent neuronal deterioration caused by increased oxidative load, thus, this study evaluated whether carvacrol administration would attenuate behavioral abnormalitie...

Bioactive compounds possess a variety of potentially beneficial bioactivities. However, the application these ingredients in food, supplement and pharmaceutical industries is often challenged due to their poor solubility, low chemical stability, unsustainable bioavailability. Carvacrol, for example, can represent wide range bioactive that are susceptible processing, transportation storage condi...

Several naturally occurring essential oils including carvacrol, anethole, cinnamaldehyde, cinnamic acid, perillaldehyde, linalool, and p-cymene were evaluated for their effectiveness in reducing decay and increasing antioxidant levels and activities in 'Duke' blueberries ( Vaccinium corymbosum). Carvacrol, anethole, and perillaldehyde showed the capability to promote total anthocyanins and tota...

Resistance to coccidiostats and possible future restrictions on their use raise the need for alternative methods of reducing coccidiosis in poultry. The aim of this study was to evaluate the effect of selected phytochemicals on Eimeria tenella sporozoite invasion in vitro. Four phytochemicals were selected on the basis that they reduce the virulence of Eimeria spp. and/or provide immune modulat...

INTRODUCTION Various methods commonly used for cleaning and shaping root canals have not been successful in completely eradicating bacteria due to anatomic complexity and root canals irregularities. Disinfecting the canals with intracanal irrigants in addition to proper cleaning and shaping can produce a successful outcome. Antimicrobials with sustained antibacterial activity would be desirable...

carvacrol is one of the main components of the eo of some labiatae (laminaceae) members like oregano, thyme and savory. carvacrol has a lot of health benefits for example, antibacterial, and antioxidant activity.we synthesized some silicon derivatives of carvacrol, and characterized them by standard methods. then the monomer of dimethylvinylsilyl carvacrol was synthesized. copolymer of this mon...

Purpose : To investigate the modulatory effect of natural phytochemical, carvacrol, on Topotecan (TOPO) cytotoxicity and cellular uptake in different cancer cell lines. Methods The carvacrol/TOPO combination therapy was determined vitro using crystal violet assay. Coomassie blue DAPI fluorescent stains were used for morphology molecular death assessments, respectively. Additionally, TOPO after ...

Escherichia coli O157: H7 es uno de los patógenos más importantes que contaminan la carne y comprometen su seguridad calidad. Los tratamientos térmicos son opción principal para garantizar inocuidad; aunque el uso barreras adicionales como adición agentes antimicrobianos, aumentan márgenes contra patógenos. En este trabajo se evaluó efecto las interacciones temperatura (55-65 °C), carvacrol (0-...

Cryptococcosis is an emerging and recalcitrant systemic infection occurring in immunocompromised patients. This invasive fungal infection is difficult to treat due to the ability of Cryptococcus neoformans and Cryptococcus laurentii to form biofilms resistant to standard antifungal treatment. The toxicity concern of these drugs has stimulated the search for natural therapeutic alternatives. Ess...