The objective of this study was to test the hypothesis that the effect of a high-fat meal (HFm) on plasma lipid-soluble antioxidants and biomarkers of vascular oxidative stress and inflammation would be attenuated by short-term lycopene supplementation in young healthy subjects. Following restriction of lycopene-containing foods for 1-wk (LYr), blood was collected in a fasting state and 3 h aft...

Obstructive sleep apnoea syndrome (OSAS) is a disorder that leads to metabolic abnormalities and increased cardiovascular risk. The aim of this study was to identify early laboratory markers of cardiovascular disease through analysis of oxidative stress in normal subjects and patients with OSAS. A prospective study was designed to compare outcomes of oxidative stress laboratory tests in 20 adul...

Ultraviolet (UV) radiation is known to cause oxidative stress and DNA damage the skin, leads premature aging. Recently, anti-aging molecules have been attracting unprecedented attention where natural ingredients present in nutraceuticals become latest trend. In this study, Abelmoschus Esculentus (i.e., okra, lady fingers) seeds (OS) were extracted using a pressurized hot water “green” method. O...

Exposure to ambient ozone causes airway hyperreactivity and lung inflammation, which represent an important health concern in humans. Recent clinical and experimental studies contributed to the understanding of the mechanisms of epithelial injury, inflammation and airway hyperreactivity, which is reviewed here. The present data suggest that ozone induced oxidative stress causes inflammasome act...

Objectives: Smoking increases oxidative modification of LDL, associated with lower HDL plasma levels, systemic inflammatory response and endothelial dysfunction. We tested the hypothesis that the risk status for coronary atherosclerosis disease (CAD) of cigarettes smokers might be identified by means of serum oxidative levels and vascular inflammation determination. Design and Methods: Oxidativ...

Background: Our aims were to investigate the time-course effects of a futsal match on performance, oxidative stress, and muscle damage markers, as well inflammatory antioxidant responses during 6-day post-match period. Methods: Thirty-four female high-level players assessed several inflammation, subjective soreness, rate perceived exertion, performance tests before match, immediately after, 24 ...

background: infertility is defined as the inability to achieve the pregnancy within a year of unprotected intercourse. infertility is a complex issue and different factors such as stress oxidative can be involved in this problem. so, any attempt to neutralize oxidative stress would be helpful in the treatment of infertility. melatonin is a known scavenger of free radicals. objective: the aim of...

Objective: The aim of the study was to explore mutual relationship between oxidative stress, inflammation and metabolic biomarkers in subjects with prediabetes (PRE), newly diagnosed type 2 diabetes patients (NT2D) overt (T2D) using principal component analysis (PCA) as a thorough statistical approach.
 Patients Methods: Glycated hemoglobin, lipid parameters, (IL-6, CRP fibrinogen) stress ...

Exposure to environmental pollutants has been recognised as a risk factor for cardiovascular events. 1-hydroxypyrene (1-OHP) is a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs) from traffic-related air pollution. Experimental studies indicate that PAH exposure could be associated with inflammation and atherogenesis. Thus, the purpose of this study was to evaluate whether the b...

Objective: Inflammation along with oxidative stress plays an important role in the development, progression, instability and rupture of coronary atherosclerotic plaques. Several studies introduced curcumin (diferuloylmethane) as a wonderful chemical in Curcuma longa<span style="font-size: m...