The aim of this study was to investigate the activity apoptosis and autophagy in animals (cows, horses, donkeys, dogs cats) naturally infected with rabies by using immunohistochemistry, immunofluorescence, qPCR. mRNA transcript levels caspase-3, Bax, Bcl2 LC3B were determined Caspase-3 AIF immunopositivity not observed immunohistochemical immunofluorescence staining, whereas intensively compare...

HIGHLIGHTS Chondrocytes express PAR-4 in the nucleus and cytoplasm; Vitamin D reduces pro-apoptotic proteins caspase-3; caspase-3 may be potential therapeutic targets for osteoarthritis.

Spinal cord injury (SCI) is a drastic disability that leads to spinal cord impairment. This study sought to determine the effects of bone marrow stem cells (BMSCs) on caspase-3 levels after acute SCI in mice. Forty-two mice were randomly divided into 3 groups: control (2 subcategories), subjected to no intervention; sham (3 subcategories), subjected to acute SCI; and experimental (2 subcategori...

Background and Aim: Smoking has been extensively investigated in oncology, controversial associations with brain tumor incidence have reported. Caspase-3 matrix metalloproteinases (MMPs) belong to an important cascade vasculogenesis. We aim study the smoking impact on these signaling molecules nontumoral rat tissue. Methods Materials/Patients: A total of 60 Wistar rats were divided into two gro...