203 words) Background Neisseria gonorrhoeae can rapidly develop resistance to antimicrobial agents. Over the last years, decreased gonococcal susceptibility to third-generation cephalosporins, especially cefixime, emerged worldwide. Therefore, current international guidelines recommend dual therapy for gonorrhoea with ceftriaxone plus either azithromycin or doxycycline. Gonococcal susceptibilit...

objective: intravascular catheter-associated infection has been increasing hospitalization in post-surgery patients mainly due to microbial colonization of the catheter surface and formation of a superficial biofilm layer. the present study is aimed in developing an effective antibacterial device which can prevent colonization of organisms by modification of catheter. methods: in the present st...

BACKGROUND Neisseria gonorrhoeae strains with resistance to extended-spectrum cephalosporins (ESCs), last options for first-line monotherapy of gonorrhoea, likely emerged and initially disseminated in Japan, followed by international transmission. In recent years, multi-locus sequence typing (MLST) ST1901 and N. gonorrhoeae multiantigen sequence typing (NG-MAST) ST1407 isolates with the mosaic ...

This investigation was carried out to evaluate the bioavailability of a new suspension formulation of cefixime (100 mg/5 ml), Winex, relative to the reference product, Suprax (100 mg/5 ml) suspension. The bio-availability study was carried out in 24 healthy male volunteers who received a single oral dose (200 mg) of the test (A) and the reference (B) products on 2 treatment days after an overni...

Nasal infection or sinusitis is an inflammation of nasal passages caused by both viral and bacteriological pathogens. Antimicrobial resistance has universally recognized as growing problem concern about suitable therapy for nasal infection. The study was aimed at determining the prevalence and antimicrobial susceptibility against nasal infecting microorganisms. 50 clinical samples were taken fr...

Background: Typhoid fever is a public health problem with high disease burden in India. The prevalence of multidrug resistance typhoid has nearly doubled from 1999 to 2005. against Fluoroquinlones very due indiscriminate use and an increased Azithromycin, one the first line antibiotics used being observed. This study will evaluate current trend antibiotic among cases observed tertiary care hosp...

Cefixime, a third-generation semi-synthetic cephalosporin antibiotic was used as copper corrosion inhibitor in 1M HNO3 solution. The study conducted through the weight loss technique at 298 - 318 K and theoretical studies based on quantum chemistry. studied drug inhibited of over cefixime concentration range (0.02 2 mM). inhibition efficiency increased with an increase to reach 91.07% mM, but d...

Background/Aim. There is no scientific evidence that the prophylactic use of antibiotics as a part mandibular third molar surgery effective in suppressing postoperative pain, edema, trismus, and dry socket. The aim study was to investigate effects from fluoroquinolone (moxifloxacin) cephalosporin (cefixime) groups reducing inflammatory sequelae (pain, trismus), well possibly incidence socket af...

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 13, No. 8, August 2007 1275 increase SLE incidence in Louisiana, and if it did increase incidence in Mississippi, the increase was minimal. In both 2003 and 2004, Louisiana’s median reporting time to ArboNET was ≈30 days. In 2005, the median reporting time prehurricane was 36 days and posthurricane was 69 days. Louisiana state offi cials bel...

INTRODUCTION Neisseria gonorrhoeae (NG) antimicrobial susceptibility trends to azithromycin, cefixime and ceftriaxone were analyzed, from 2009 to 2016, to monitor changing antimicrobial susceptibility concomitant with the change in prescribing practice in 2012 from cefixime, or ceftriaxone, to ceftriaxone plus azithromycin. Patient characteristics predictive to be infected by antibiotic resista...