Hereditary spherocytosis and elliptocytosis are the two most common inherited red cell membrane disorders resulting from mutations in genes encoding various red cell membrane and skeletal proteins. Red cell membrane, a composite structure composed of lipid bilayer linked to spectrin-based membrane skeleton is responsible for the unique features of flexibility and mechanical stability of the cel...

nowadays, growing interest in the application of nanotechnology in biomedical and biotechnological fields has opened a new avenue to explore the nanoparticles-biological system interaction. indeed, a clear gap is still in the cytotoxic effect of nps on the biological systems. for this purpose, the interaction of the silica oxide nanoparticles (sio2-np) with pc12 cell line, as a model of nervous...

background: nowadays, highly specific aptamers generated by cell selex technology (systematic evolution of ligands by exponential enrichment) are being applied for early detection of cancer cells. prostate specific membrane antigen (psma), over expressed in prostate cancer, is a highly specific marker and therefore can be used for diagnosis of the prostate cancer cells. the aim of the present s...

Five alfalfa (Medicago sativa L) cultivars from different areas of Iran were evaluated for oxidative markers under salinity conditions. Plants were grown in hydroponic condition by Hoagland nutrient solution containing different amounts of NaCl (control, 50 and 100 mM). Relative growth rate, membrane stability, lipid peroxidation, proline, hydrogen peroxide and relative water contents were dete...

Metal-organic frameworks (MOFs) are emerging material class for the past few years due to its tailorability characteristics for various applications. However, the research and development (R&D) of MOFs is still scarce for fuel cell system. This may be due to the several difficulties faced in selecting a good MOFs-based electrolyte, which consequently affects both proton conduction and methanol ...

in present research work, homogeneous anion exchange membranes based on polysulfone (qapsfs) were prepared via chloromethylation, amination and alkalization. in amination step, trimethylamine and n,n,n',n'-tetramethyl-1,6-hexanediamine were used as amination and crosslinking agents, respectively. the chloromethylated polysulfone was characterized by 1hnmr spectroscopy and chloromethylation degr...

mitochondrial functions have a major impact on t-cell functionality. in this study we characterized whether mitochondrial function in the neonatal t-cells differs from that in the adult t-cells during short t-cell activation. methods: we used fow cytometry methods to test mitochondrial mass and to monitor mitochondrial ca2+ levels, mitochondrial potential and superoxide generation in parallel w...