Latest research on biological systems is steadily shifting from isolated single cells to entire cell populations. The latter are inherently heterogeneous, and their modeling requires approaches that explicitly account for this property. A comprehensive such approach is the cell population balance (CPB), which, however, is computationally expensive and becomes intractable for multivariable model...

A theoretical model is developed to consider the effect of demulsifier agent on demulsification of water-in-crude oil emulsion. A thermodynamic approach is considered to correlate the critical micelle concentration of a demulsifier to the collision frequency function in population balance equation (PBE). Based on the proposed correlation, the collision frequency function is modified to account ...

Background: Mosaicism of a normal cell population and an unbalanced autosomal chromosome rearrangement is rarely seen. If the abnormal cell line contributes to a minor part of soma, the phenotype is expected to be normal. Case Report: We report a 29-year-old woman who had balance chromosomal translocation of 46,XX,t(5;21) with a 2-year-old affected girl, characterized by mental retardation, dys...

Population balance modeling is undergoing phenomenal growth in its applications, and this growth is accompanied by multifarious reviews. This review aims to fortify the model's fundamental base, as well as point to a variety of new applications, including modeling of crystal morphology, cell growth and differentiation, gene regulatory processes, and transfer of drug resistance. This is accompli...