introduction: oxidative stress and neuroinflammation are involved in neurodegeneration procedure in parkinson’s disease. recently, neuroprotective potential of boswellia resin has been demonstrated. therefore, this study examined whether administration of boswellia resin would attenuate mpp+- induced neuronal death in sk-n-sh- cell line, a human dopaminergic neurons- in vitro. methods: boswelli...

Background and Aim: Implant site preparation with minimal trauma is an important factor in success of implant treatment and has a great effect on osseointegration. Piezoelectric bone surgery was introduced as a modern technique for micrometric osteotomy with precise, controllable action. Preservation of osteoblast cell viability is critical to achieve successful osseointegration. The present st...

Background: Breast cancer is the most prevalent malignancy among women in the worldwide and the outbreak in Iranian women is growing. Iranian patients with breast cancer are younger than their Western counterparts. Dracocephalum kotschyi is a wild-growing flowering plant belonging to the family Labiatae and found in Iran. This plant has been applied in Iran folk medicine. The aim of this study ...

Background: Cancer refers to the abnormal growth of cells and is still the most common cause of morbidity in world. The purpose of this study was to determine cytotoxicity effect of high molecular weight (HMWC) and low molecular weight of chitosan (LMWC) on three cancerous cell lines MCF-7, HeLa and Saos-2 with different histological origin. Methods: The anticancer property of two types of chi...

we investigated the effects of 25 mg-porphyrin-fullerene nanoparticles, ( 25 mgpmc16) smart ferroporphyrin nanoparticles, on pc12 cells exposed to oxygen-glucose deprivation/reperfusion. in order to explore its effect on cells under oxygen-glucose deprivation conditions, the cultures were pretreated with 25 mgpmc16 24 hours prior to oxygen-glucose deprivation/reperfusion. to initiate the oxygen...

objective: hydrostatic pressure is crucial component of cell environment and fundamental physical quantity, also it is the main factor of both cell integrity and function. pressure variation disorder, beyond physiological limits, may lead to pathological states. in this study, we examined the effect of hydrostatic pressure on apoptosis induction, viability, morphology, adhesion potency to subst...