Obesity is a primary risk factor for the development of obstructive sleep apnea in humans, but the impact of obesity on central sleep apnea is less clear. Given the comorbidities associated with obesity in humans, we developed techniques for long-term recording of diaphragmatic EMG activity and polysomnography in obese mice to assess breathing patterns during sleep and to determine the effect o...

BACKGROUND Central adiposity as an indicator of visceral fat is linked to vascular and metabolic factors that in turn are related to cognitive decline and dementia. OBJECTIVE To determine whether larger waist-hip ratio (WHR) is associated with structural brain changes that underlie cognitive decline and dementia. DESIGN Cross-sectional analysis of an epidemiologic cohort study of cognitive ...

Inconsistent associations between dietary glycaemic index (GI) and glycaemic load (GL) and body fatness may be partly due to differences in the underlying dietary patterns or energy under-reporting. In the present study, we examined the cross-sectional associations of dietary GI and GL with food and nutrient intake and general and central obesity, accounting for energy under-reporting. The subj...

BACKGROUND Emerging evidence suggests that neighborhood characteristics can have direct and indirect effects on the weight status of the residents. OBJECTIVES To assess the relationship between general and central obesity and the neighborhood environment in two ethnic groups (Azeri Turks and Kurds) living in Urmia city, Northwestern Iran. PATIENTS AND METHODS In this cross-sectional study, ...

background: cardiovascular disease is a major cause of death throughout the world. the aim of this study was to as­sess the prevalence of overweight/obesity, central obesity, hypertension and dyslipidemia, as well as dietary factors contribut­ing to the development of dyslipidemia among middle-aged women. methods: the research design of the present study was a population-based cross-sectional s...

Obesity markedly increases the odds of developing depression. Depressed mood not only impairs motivation, quality of life and overall functioning but also increases the risks of obesity complications. Abdominal obesity is a better predictor of depression and anxiety risk than overall adipose mass. A growing amount of research suggests that metabolic abnormalities stemming from central obesity t...

BACKGROUND Low calcium:phosphorus ratios (Ca:P ratio) in habitual diet have been observed worldwide, and it has been shown to be harmful to the bone health of the population. However, no study associating this ratio with obesity was found. Thus, considering that the intake of calcium and phosphorus will generate a ratio between them, which may be associated with obesity, this research seeks at ...

OBJECTIVE To analyze if differences according to gender exists in the association between tooth loss and obesity among older adults. METHODS We analyzed data on 1,704 older adults (60 years and over) from the baseline of a prospective cohort study conducted in Florianopolis, SC, Southern Brazil. Multivariable logistic regression models were used to assess the association between tooth loss and ...

1The Third Department of International Medicine, Tokyo Medical University 2Division of Health and Nutrition Monitoring, National Institute of Health and Nutrition 3Division of Human Nutrition, National Institute of Health and Nutrition 4Department of Geriatric Disease Medicine, University of Tokyo 5International Diabetes Institute (Australia) 6Department of Nutrition and Physiology, Kyoritsu Wo...

Although generalized obesity is a risk factor for all of the life-threatening diseases that I have described, the accumulation of excess body fat within and around the abdomen (central obesity) appears to be linked with an especially high risk of obesity-associated illnesses. Now, a new research study, just published in the journal Neurology, suggests that dementia may also be more common among...