Obesity is a major health issue in the developed nations, and it has been increasingly clear that both genetics and environment play an important role in determining if an individual will be obese or not. We reviewed the latest researches which were carried out to identify the obesity susceptible genes and to identify the metabolic pathways having a central role in energy balance. Obesity is a ...

OBJECTIVE To investigate predictors of adolescent obesity in rural South Africa. DESIGN Cross-sectional study. Height, weight and waist circumference were measured using standard procedures. Overweight and obesity in adolescents aged 10-17 years were assessed using the International Obesity Taskforce cut-offs, while the WHO adult cut-offs were used for participants aged 18-20 years. Waist-to-...

While many women with polycystic ovary syndrome (PCOS) are overweight, obese or centrally obese, the effect of excess weight on the outcomes of PCOS is inconsistent. The review aimed to assess the effects of overweight, obesity and central obesity on the reproductive, metabolic and psychological features of PCOS. MEDLINE, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL) ...

OBJECTIVE To evaluate peripheral respiratory system resistance and reactance (Rrs and Xrs, respectively) in obese individuals. METHODS We recruited 99 individuals, dividing them into four groups by body mass index (BMI): < 30.0 kg/m2 (control, n = 31); 30.0-39.9 kg/m2 (obesity, n = 13); 40.0-49.9 kg/m2 (severe obesity, n = 28); and ≥ 50.0 kg/m2 (morbid obesity, n = 13). Using impulse oscillom...

BACKGROUND Obesity leads to increased risk of cardiovascular disease and glucose intolerance, which are phenomena of chronic inflammation. This study was performed to determine whether a higher body mass index (BMI) and central obesity are associated with low-grade inflammation. METHODS An analysis of 8 453 adults aged > or =20 years was performed. Every subject completed a household intervie...

BACKGROUND Obesity is a major determinant of cardiovascular disease in South America. However, population-based data are limited. METHODS A total of 7,524 women and men, aged 35 to 74 years old, were randomly selected from 4 cities in the Southern Cone of Latin America between February 2010 and December 2011. Obesity clinical measurements and cardiovascular risk factors were measured using st...

Background: Obesity has been identified as the most important modifiable risk factor in the aetiology of type-2 diabetes mellitus. In clinical practice, body mass index (BMI) is the commonest index used to define the presence and degree of obesity. Unfortunately, BMI does not define the presence or absence of central obesity which has been shown to be the most pathogenically important in the ca...

BACKGROUND The role of excessive adiposity or its metabolic consequences in persistent HPV infection among general adult women remains unknown. METHODS Using data from the National Health and Nutrition Examination Survey (NHANES) in 2003-2010, we compared adult women's likelihood for any- or high-risk (HR) type HPV infection by degrees of excessive adiposity and metabolic health status. RES...

BACKGROUND AND AIM There is currently no published study comparing prevalence of non-alcoholic fatty liver disease (NAFLD) and associated factors among diabetics of different ethnicity in the Asia-Pacific region. METHODS Cross-sectional study of consecutive patients in the Diabetic Clinic in University of Malaya Medical Centre. The Global Physical Activity Questionnaire and a semiquantitative...