BACKGROUND/AIM Telomerase activity is influenced by hTERT transcriptional regulation, shelterin, and posttranscriptional alternative splicing. Telomerase shelterin such as POT1 is highly correlated with various cancers. However, the profile of POT1 in cervical cancer has not been clearly identified. Therefore, it is important to identify its profile in cervical cancer biopsy tissue and normal c...

Cervical cancer tends to occur at an early age. Treatment for cervical cancer includes surgery, chemotherapy, radiotherapy or their combination. The 2-year survival of early cervical cancer after surgery or chemoradiothearpy reaches over 80%. Stage Ib2 cervical cancer, however, is a high-risk early stage cervical cancer with easy recurrence and metastasis. Its 5-year survival is as low as about...

INTRODUCTION Despite the wide-spread availability of cervical cancer prevention and screening programs in developed countries, the morbidity and mortality rates of cervical cancer in Zimbabwe are still very high. Limited resources as well as the high HIV prevalence are contributors to the high burden of cervical cancer. This paper aims to analyse the policies, frameworks and current practices i...

abstract carcinoma of the cervix is a common neoplasm and accounts for a considerable number of cervical diseases that lead to death in developing countries. in these countries early detection and improved methods of treatment have resulted in comparatively better control of the cancer and long survival however, invasive and metastatic disease still occurs. the authors present the case report o...

This study was undertaken to evaluate knowledge about HPV infection and cervical cancer among nurses in Chiang Mai University Hospital, Thailand. The 16 questions evaluating knowledge were 'true/false/do not know' type. Two hundred and twenty nurses agreed to participate in this survey. Most knew that cervical cancer is the most common female cancer in Thailand (92.7%), HPV infection is a causa...

Cervical cancer is the second most common cancer in women worldwide after breast cancer. There are about 500,000 new cases and 250,000 deaths due to cervical cancer each year. Almost all cervical cancer cases (99%) are caused by human papillomavirus (HPV) infection (World Health Organization 2006). In Malaysia, the age standardized incidence rate (ASR) for cervical cancer is 19.7 per 100,000 wo...

Cervical cancer is a treatable and preventable cancer that remains a concern for women worldwide. Efforts to reduce rates of cervical cancer focus on the promotion of human papillomavirus (HPV) vaccination and the promotion of routine recommended cervical cancer screening, primarily done by cervical cytology and cervical HPV testing. Recently researchers have begun to examine urine-based HPV te...

Cysteine-X-cysteine ligand 8 (CXCL8) was originally discovered as a proinflammatory chemokine. Recently, CXCL8 has been shown to act as an oncogene in several types of human cancers. However, the clinical and prognostic significance of CXCL8 in cervical cancer is poorly understood. In our study, we found that CXCL8 was highly expressed in cervical cancer tissues compared with normal cervical ti...

BACKGROUND We sought to develop and validate a decision-analytic model for the natural history of cervical cancer for the German health care context and to apply it to cervical cancer screening. METHODS We developed a Markov model for the natural history of cervical cancer and cervical cancer screening in the German health care context. The model reflects current German practice standards for...