نتایج جستجو برای: cgrp cox
تعداد نتایج: 51768 فیلتر نتایج به سال:
introduction: dental pulp has neural fibers that produce neuropeptides like substance p (sp) and calcitonin gene-related peptide (cgrp). the inflammation of dental pulp can lead to an increase amount of sp and cgrp release, especially in symptomatic irreversible pulpitis. therefore, it can be assumed that neuropeptides have some role in the progression of inflammation of the dental pulp. the ai...
Objective: Concerning the possible role of CGRP in NMJ, the aim of this research was to study the effect of an endurance training program on relative content of this neuropeptide in NMJ, of fast plantaris and slow Soleus muscles of female rats. Methods: The end plates were identified by FITCc-labled - α -bungarotoxin and relative content of CGRP of never endings were determined by Immunohisto...
مقدمه: پپتید مرتبط به ژن کلسیتونین (CGRP) یک نوروپپتید 37 اسید آمینهای است که توسط فرایند ویژهی بافتی از ژن کلسیتونین تولید میشود و تولید عمدهی آن در بافتهای اعصاب مرکزی و محیطی گونههای مهرهداران و غیرمهرهداران است. CGRP در سازگاریهای پیوندگاه عصبی ـ عضلانی نقش مهمی دارد. در این پژوهش اثر تمرینهای استقامتی و مقاومتی بر میزان CGRP در عضلات تند انقباض (درشت نی قدامی) و کند انقباض ...
Calcitonin gene-related peptide (CGRP) receptors are classified into CGRP subtype 1 (CGRP(1)) and CGRP subtype 2 (CGRP(2)) based on the affinity of the antagonist, human alpha (halpha)-CGRP(8-37). halpha-CGRP(8-37) antagonizes CGRP(1) receptor-mediated responses with high affinity (K(B) < 100 nM) and antagonizes CGRP(2) receptor-mediated responses with low affinity (K(B) > 1 microM). CGRP(2) re...
The calcitonin gene-related peptide (CGRP) has been demonstrated relating to vascular and inflammatory regulations not only the nerve systems. As anti-inflammation factor most potent vasodilator, CGRP holds therapeutic potentials for treatment of cardiovascular diseases which was, however, limited by its nature short half-life. With advantages in improving stability, circulation time protection...
objective(s) recent studies on human indicate that the introduction of therapeutic use of tolerogenic dendritic cell (dc) for chronic inflammatory conditions is imminent. for the purpose of defining cgrp potency in tolerogenic dc production, we investigated the phenotype and il-'2 production of dcs generated from the monocytes of rheumatoid arthritis (ra) patients in the presence of the ca...
هدف از این مطالعه تعیین تاثیر تخلیه گلیکوژنی بر پاسخ cgrp در حین تمرین استقامتی و اثر احتمالی لاکتات بر آزاد سازی آن در شرایط استراحت بود. 10 نفر دانشجوی مرد فعال تربیت بدنی با میانگین سن 67/1±4/22، وزن 56/5 ± 28/71 و شاخص توده بدنی 07/1 ± 31/23 به صورت هدفمند انتخاب و در 4 وهله مجزا با حداقل فاصله زمانی یک هفته 4 آزمون جهت سنجش pmax، انجام فعالیت استقامتی حاد پس از تخلیه گلیکوژن (کوشش تخلیه)، ...
Induction of cyclooxygenase-2 (COX-2) in the renal pelvic wall increases prostaglandin E(2) (PGE(2)) leading to stimulation of cAMP production, which results in substance P (SP) release and activation of renal mechanosensory nerves. The subtype of PGE receptors involved, EP2 and/or EP4, was studied by immunohistochemistry and renal pelvic administration of agonists and antagonists of EP2 and EP...
It is known that the neural system plays a fundamental role in neovascularization. A neuropeptide, calcitonin gene-related peptide (CGRP), is widely distributed in the central and peripheral neuronal systems. However, it remains to be elucidated the role of CGRP in angiogenesis during ischemia. The present study examined whether endogenous CGRP released from neuronal systems facilitates revascu...
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