نتایج جستجو برای: chalcone
تعداد نتایج: 2361 فیلتر نتایج به سال:
A new strategy which uses very cheap FeCl3 as an effective catalyst in the presence of Me3SiCl has been developed for the conjugate addition of enones and chalcone with unactivated weakly nucleophilic carbamates.
An efficient and facile green synthesis of chalcone derivatives 1a-d was achieved by treatment aromatic aldehydes with 2-acetylthiophene in the presence choline chloride-urea mixture as a deep eutectic solvent. Chalcone 1a used reactive key precursor to design series bio-active heterocycles such pyrimidine, pyrazoline, pyridine, pyridopyrimidine naphthyridine. The Structural formula were confir...
In the title chalcone derivative, C(17)H(15)BrO, the dihedral angle between the two benzene rings is 48.13 (4)°. In the crystal, a short Br⋯Br contact of 3.5052 (10) Å occurs.
A series of novel chalcone-1,2,3-triazole-azole hybrids were designed, synthesized and evaluated for their antiproliferative activity against three selected cancer cell lines (SK-N-SH, EC-109 and MGC-803). Most of the synthesized compounds exhibited moderate to good activity against all the cancer cell lines selected. Particularly, compound I-21 showed the most excellent antiproliferative activ...
Leaves of a novel strain of peas (Pisum sativum L.) were used to determine the distribution of secondary metabolites and their biosynthetic enzymes. Leaf epidermal layers in this strain are easily separated from the parenchyma. Anthocyanins and flavonol glycosides were localized in epidermal vacuoles only. Among the biosynthetic enzymes studied, phenylalanine ammonia-lyase (PAL, EC 4.3.1.5), S-...
A chalcone was prepared by the reaction of terephthalaldehyde with 3-acetyl-2,5-dimethylthiophene. Treatment of this chalcone with thiosemicarbazide/phenyl hydrazine/guanidine hydrochloride/thiourea afforded the corresponding pyrazoline, pyrazole, and pyrimidine in good yields. All the new compounds have been characterized by IR, 1H-NMR, 13C-NMR, GC-MS and elemental analyses. The anti-bacterial...
With the aim of finding new chemical entities based on coumarin and chalcone scaffolds, new hybrid compounds 2-5 were designed and synthesized. The trypanocidal activity of these compounds was tested against the epimastigote, trypomastigote and amastigote stages of the Trypanosoma cruzi parasite. Cytotoxicity assays were also performed in RAW 264.7 and VERO cells. Compound 5 presented the highe...
Herein we present a photoreactive chalcone moiety that can be synthesized at scale of several grams with ease, and efficiently undergo [2 + 2] photocycloaddition light close to 500 nm as determined by an action plot.
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