ATP-sensitive potassium (KATP) channel openers have a relaxation effect due to the lower cellular membrane potential and inhibit calcium influx. There has been considerable interest in exploring KATP channel openers in the treatment of various diseases such as cardiovascular, cerebrovascular, and urinary system disease and premature labor. The purpose of this study was to synthesize 3,3,6,6-tet...

steam reforming integrated with oxidation of methanol was considered with numerical simulation. the parallel micro-channels with circular cross sections were used. because when the catalytic deposited inside the rectangular micro-channels, it fills up the edges. hence, the approximation of a cylindrical channel is appropriate. effect of this changing in cross section was considered and results ...

ion channels are naturally occurring pores through the proteins that regulate the passage of ions and thus maintain the concentration of ions inside and outside the cell. the ion channels control many physiological functions and they can show selectivity for a specific ion. ion channels are mostly observed in nerve cells and muscle cells. the influx of ions into cells can be regulated by a gate...

several studies suggest that invertebrate abundance and richness are disrupted and reset at confluences. thus, junctions contribute disproportionately to the overall aquatic biodiversity of the river. in general terms, authors have reported high abundance and diversity due to the major physical heterogeneity at junctions. however, data are still scarce and uncertainties are plentiful.the impact...

objective(s) calcium-channel blockers have an important role in the treatment of several cardiovascular disorders. derivatives of 1, 4-dihydropyridine are one of the most potent calcium antagonists. in this study four novel ', 4-dihydropyridine calcium channel blockers were synthesized and their hypotensive properties were investigated in male rats. materials and methods four 1, 4-dihydrop...

this paper concerns the transmission of two independent gaussian sources over a two-user decentralized interference channel, assuming that the transmitters are unaware of the instantaneous csis. the availability of the channel state information at receivers (csir) is considered in two scenarios of perfect and imperfect csir. in the imperfect csir case, we consider a more practical assumption of...

the incidence of microbial keratitis after intacs implantation is extremely low and channel infection has been infrequently reported. we present a 23-year-old woman with keratoconus of both eyes who underwent implantation of two intrastromal corneal ring segments (intacs, keravision, inc., fremont, ca, usa) in the right eye. after 2.5 months, the patient presented with decreased vision, inflamm...

most previous laboratory studies of local scour at bridge abutments were performed in rectangular channels in which the distributions of flow velocity and bed shear stress were considered uniform in the transverse direction. in reality however, bridge abutments are usually located in the floodplain zone of rivers where velocity and shear stress distributions are directly affected by the lat...