▶ Offers original research papers on condensed and gaseous states of matter ▶ Spans artificial divisions in current literature among the areas of structure determination, energetics, and applications ▶ Offers broad discussion of results, observation of relationships among various properties, and applications of structure and energy information in all domains of chemistry ▶ 97% of authors who an...

Tetrathiafulvalene (TTF) is a fascinating system: it is quite rare to find a synthetic molecule endowed with such a simple architecture that is capable of concentrating intense interest from various communities of chemists! This modest-sized molecule which consists of only 14 atoms, was synthesized in the early nineteen seventies [1-3] and since then has proved to be exceptionally popular in va...

In the 17century, German miners discovered a red coloured ore they believed to contain copper. They discovered upon analysis that there was no copper but that a useless, smelly material was actually present. Thinking the ore was evil they dubbed it "Kupfernickel" or Old Nick's Copper, which meant false or bad copper. Swedish scientist Baron Axel Frederich Cronstedt in 1751 finally isolated nick...

Several cases are described in which the chelate effect contributes to binding and catalysis. In the first examples, dimers made up of linked cyclodextrins show very strong selective substrate binding, and with catalytic groups in the linkers they are effective catalysts of reactions of bound substrates. In later examples, chelate binding of transition states by a base and an acid produce effec...

▶ Offers original research papers on condensed and gaseous states of matter ▶ Spans artificial divisions in current literature among the areas of structure determination, energetics, and applications ▶ Offers broad discussion of results, observation of relationships among various properties, and applications of structure and energy information in all domains of chemistry ▶ 97% of authors who an...

An information processing system is described which is inspired by the processing of molecules within cells under the control of enzymes. The system is shown to be capable of being configured to carry out a simple information processing task, namely sorting a set of numbers into an ordered list. Results of the time evolution of the system carrying out this task are presented. A framework is des...

Organophosphorus compounds are ubiquitous in nature, and due to their innate chemical properties, serve a fundamental role in a number of important fields. Among the more prominent features that elevate their status as a unique and versatile class of compounds, include variable oxidation states, multivalency, asymmetry and metal-binding properties. Their presence in bioactive natural products, ...

Telomerase is a promising “universal” anticancer target. It has been demonstrated that inhibition of telomerase leads to mortalization and death of previously immortal cell lines. We are interested in targeting telomerase by binding to the RNA/DNA duplex that forms during its catalytic cycle. The RNA strand of this duplex is a component of telomerase and acts as a template to direct the synthes...