نتایج جستجو برای: chitosan

تعداد نتایج: 17212  

Journal: :Biomaterials 2012
Kentaro Hozumi Ayano Sasaki Yuji Yamada Dai Otagiri Kazuki Kobayashi Chikara Fujimori Fumihiko Katagiri Yamato Kikkawa Motoyoshi Nomizu

Laminin-111, a multifunctional matrix protein, has diverse biological functions. Previously, we have identified various biologically active sequences in laminin-111 by a systematic peptide screening. We also demonstrated that peptide-conjugated chitosan matrices enhance the biological functions of the active sequences and are useful as a scaffold. Here, we conjugated sixty biologically active l...

2017
Anish Babu Rajagopal Ramesh

Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chitosan has multifaceted applications, such as assisting in gene delivery and chemotherapeutic delive...

Journal: :Journal of microencapsulation 2006
K G Desai H J Park

To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentration and volume of 1% w/v TPP solution) had a significant influence on the charac...

Journal: :Molecules 2017
Hellen Franciane Gonçalves Barbosa Maha Attjioui Ana Paula Garcia Ferreira Edward Ralph Dockal Nour Eddine El Gueddari Bruno M Moerschbacher Éder Tadeu Gomes Cavalheiro

In an attempt to enhance chitosan biological activities, biopolymeric Schiff bases of chitosan and different salicylaldehydes and their palladium(II) and platinum(II) complexes were synthesized and tested. The chemical structures of these derivatives were characterized using ¹H-NMR, FTIR spectroscopy and XPRD. Thermal analysis was done through TGA/DTG-DTA. Electronic absorption spectra and surf...

2013
Huiying Chen Shaohui Cui Yinan Zhao Bing Wang Shubiao Zhang Xiaojun Peng

An in-situ reactor was elaborately designed for O-alkylation of chitosan in an ionic liquid ([BMIM]Cl) solvent, using N, N'-carbonyldiimidazole as bonding agent. The original chitosan and the modified chitosan were characterized by FT-IR and XRD analysis. FT-IR spectra revealed that the alkylation of chitosan selectively occurred at hydroxyl groups, with unprotected amino groups untouched. It w...

2017
Likun Liu Yi Xin Jia Liu Ershao Zhang Weiling Li

BACKGROUND Chitosan oligosaccharide, the degradation products of chitin, was reported to have a wide range of physiological functions and biological activities. In this study, we explored the inhibitory effect of Chitosan oligosaccharide on human hepatoma cells. MATERIALS AND METHODS MTT assay was applied to detect cell viability of the human hepatoma cells treated with Chitosan oligosacchari...

Journal: :Biomaterials 2005
Thomas Freier Hui Shan Koh Karineh Kazazian Molly S Shoichet

As part of our ongoing effort to develop a biodegradable nerve guidance channel based on chitin/chitosan, we conducted a systematic in vitro study on the biodegradation and neural cell compatibility of chitosan and N-acetylated chitosan. The in vitro degradation (pH 7.4, 37 degrees C) in the presence of 1.5 microg/ml lysozyme showed a progressive mass loss to greater than 50% within 4 weeks for...

2014
Fatemeh Ajalloueian Hossein Tavanai Jöns Hilborn Olivier Donzel-Gargand Klaus Leifer Abeni Wickham Ayyoob Arpanaei

Novel nanofibers from blends of polylactic-co-glycolic acid (PLGA) and chitosan have been produced through an emulsion electrospinning process. The spinning solution employed polyvinyl alcohol (PVA) as the emulsifier. PVA was extracted from the electrospun nanofibers, resulting in a final scaffold consisting of a blend of PLGA and chitosan. The fraction of chitosan in the final electrospun mat ...

2016
Bi Foua Claude Alain Gohi Hong-Yan Zeng A Dan Pan

Pepsin was used to effectively degrade chitosan in order to make it more useful in biotechnological applications. The optimal conditions of enzymolysis were investigated on the basis of the response surface methodology (RSM). The structure of the degraded product was characterized by degree of depolymerization (DD), viscosity, molecular weight, FTIR, UV-VIS, SEM and polydispersity index analyse...

2017
Hashem Rasti Kazem Parivar Javad Baharara Mehrdad Iranshahi Farideh Namvar

This study presents the first ever data of extracting chitin from the Chiton shell, which was then converted to the soluble chitosan by soaking in the 45% NaOH solution. The obtained chitin and chitosan were characterized by the seven different methods. Antioxidant activity of the extracted chitosan was also evaluated using the two methods. The shell content was divided into calcium carbonate (...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید