نتایج جستجو برای: chitosan

تعداد نتایج: 17212  

2015
M. Pogorielov O. Kalinkevich V. Deineka V. Garbuzova A. Solodovnik A. Kalinkevich T. Kalinichenko A. Gapchenko A. Sklyar S. Danilchenko

BACKGROUND Chitosan and its derivates are widely used for biomedical application due to antioxidative, anti-inflammatory, antimicrobial and tissue repair induced properties. Chitosan-based materials also used as a haemostatic agent but influence of different molecular weight and concentration of chitosan on biological response of blood cells is still not clear. The aim of this research was to e...

Journal: :Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2008
Koji Oshita Toshio Takayanagi Mitsuko Oshima Shoji Motomizu

Catechol-type chitosan resin and salicylic acid-type chitosan resin were easily synthesized for use in estimating the adsorption behavior of 34 elements at pH 1 - 7 in aquatic media. The catechol-type chitosan resin could adsorb Cu(II) at pH 3 - 7, In(III) at pH 4 - 6, Pb(II) and lanthanoids at pH 5 - 7, and U(VI) at pH 4 - 7 more effectively than the salicylic acid-type chitosan resin and the ...

Journal: :Molecules 2017
Byungman Kang Temmy Pegarro Vales Byoung-Ki Cho Jong-Ki Kim Ho-Joong Kim

In this work, antioxidant hydrogels were prepared by the construction of an interpenetrating chitosan network and functionalization with gallic acid. The poly(2-hydroxyethyl methacrylate) p(HEMA)-based hydrogels were first synthesized and subsequently surface-modified with an interpenetrating polymer network (IPN) structure prepared with methacrylamide chitosan via free radical polymerization. ...

Journal: :International journal of cancer 2011
Jue-Yeon Lee Young-Suk Choi Jin-Sook Suh Young-Min Kwon Victor C Yang Seung-Jin Lee Chong-Pyoung Chung Yoon-Jeong Park

In this study, a cell-penetrating peptide, the transactivating transcriptional factor (TAT) domain from HIV, was linked to a chitosan/doxorubicin (chitosan/DOX) conjugate to form a chitosan/DOX/TAT hybrid. The synthesized chitosan/DOX/TAT conjugate showed a different intracellular distribution pattern from a conjugate without TAT. Unlike both free DOX and the conjugate without TAT, the chitosan...

2017
Chen-Yuan Chiu Shih-An Feng Shing-Hwa Liu Meng-Tsan Chiang

The present study investigated and compared the regulatory effects on the lipid-related metabolism and intestinal disaccharidase/fecal bacterial enzyme activities between low molecular weight chitosan and chitosan oligosaccharide in high-fat-diet-fed rats. Diet supplementation of low molecular weight chitosan showed greater efficiency than chitosan oligosaccharide in suppressing the increased w...

2011
James C.K. Lai Wenjuan Gao Solomon W. Leung

We have systematically examined the effects of chitosan film or chitosan in combination with nanometal particles (nanogold or nanosilver particles) on the growth of Schwann cells (S16) and DRG neurons (50B 11). Our results strongly suggest chitosan and chitosan in combination with nanogold particles had no effects on the growth kinetics of Schwann cells but had slightly slowed those of DRG neur...

2015
Oana Maria Dragostin Sangram Keshari Samal Florentina Lupascu Andreea Pânzariu Peter Dubruel Dan Lupascu Cristina Tuchilus Cornelia Vasile Lenuta Profire Hitoshi Sashiwa

The objective of this study was to develop new films based on chitosan functionalized with sulfonamide drugs (sulfametoxydiazine, sulfadiazine, sulfadimetho-xine, sulfamethoxazol, sulfamerazine, sulfizoxazol) in order to enhance the biological effects of chitosan. The morphology and physical properties of functionalized chitosan films as well the antioxidant effects of sulfonamide-chitosan deri...

2007
Yi Hu Yangzhe Wu Jiye Cai Yufeng Ma Bin Wang Ke Xia Xiaoqing He

In this paper, we investigated the self-assembly and fractal feature of chitosan and Ag (I), Cu (II)-chitosan due to the theoretical and practical importance of chitosan in biomedical engineering, biomaterials and environmental sciences etc. The self-assembly and fractal structures of chitosan and Ag (I), Cu (II)-chitosan were observed using atomic force microscope (AFM), and the fractal dimens...

2018
Xiaoying Kong Wenhua Xu Cuiping Zhang Wei Kong

In the present study, a temperature-sensitive gel composed of chitosan, carboxymethyl chitosan and glycerophosphate was prepared and loaded with chitosan microspheres encapsulating levofloxacin. The bioavailability of levofloxacin and the safety of this novel opthalmic drug delivery formulation were evaluated. Levofloxacin chitosan microspheres were prepared using the ionic gelation method, and...

2017
Estefânia V. R. Campos Jhones L. Oliveira Leonardo F. Fraceto

Chitosan, a polyaminosaccharide obtained by alkaline deacetylation of chitin, possesses useful properties including biodegradability, biocompatibility, low toxicity, and good miscibility with other polymers. It is extensively used in many applications in biology, medicine, agriculture, environmental protection, and the food and pharmaceutical industries. The amino and hydroxyl groups present in...

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