Prosthetic joint infection (PJI) is a serious complication after total joint arthroplasty (TJA). Chlorhexidine is a widely used antiseptic because of its rapid and persistent action. It is well tolerated and available in different formulations at various concentrations. Chlorhexidine can be used for pre-operative skin cleansing, surgical site preparation, hand antisepsis of the surgical team an...

background and aims. streptococcus mutans is the main pathogenic agent involved in dental caries, and may be eliminated using mouthwashes. the objective of this study was to compare the effects of fluoride, chlorhexidine, and fluoride-chlorhexidine mouthwashes on salivary s. mutans count after two weeks of use and determine the prevalence of their side effects on the oral mucosa. materials and ...

OBJECTIVES This study aimed to evaluate the capacity of 2% chlorhexidine gel associated with 8% papain gel in comparison with 5.25% sodium hypochlorite in bovine pulp tissue dissolution. MATERIALS AND METHODS Ninety bovine pulps of standardized sizes were used and fragmented into 5-mm sizes. The fragments were removed from the root middle third region. They were divided into 6 experimental gr...

Background and Aim: This study was designed to explore the clinical utility of apricot kernel decoction on salivary glycoproteins in patients with periodontitis. Methods: The samples were obtained from 123 subjects divided into 4 groups, namely healthy individuals (healthy), non-treated periodontitis (control), chlorhexidine-treated (chlorhexidine) both (decoction + chlorhexidine). Salivary sia...

This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate. Skin permeation studies were performed on full-thickness human skin using Franz diffusion cells with exposure to chlorhexidine for 2 min, 30 min, and 24 h. The concentration of c...

BACKGROUND In infected periapical tissues, Enterococcus faecalis is one of the most common dominant bacteria. Chlorhexidine has been proved to show strong antibacterial ability against E. faecalis but is ineffective in promoting mineralization for tissues around root apex. Mesoporous calcium-silicate nanoparticles are newly synthesized biomaterials with excellent ability to promote mineralizati...

The chlorhexidine resistance of 317 strains of Pseudomonas aeruginosa isolated from hospital patients was determined. The distribution pattern of their susceptibility to chlorhexidine clearly revealed two peaks, and the frequency of resistance to chlorhexidine was 84.2%.

OBJECTIVE To demonstrate whether daily bathing with cloths impregnated with 2% chlorhexidine gluconate will decrease colonization of resistant bacteria and reduce the rates of health care-associated infections in critically injured patients. DESIGN Retrospective analysis of data collected 6 months before and after institution of a chlorhexidine bathing protocol. SETTING A 12-bed intensive c...

BACKGROUND Ventilator-associated pneumonia is associated with increased morbidity and mortality. OBJECTIVE To examine the effects of mechanical (toothbrushing), pharmacological (topical oral chlorhexidine), and combination (toothbrushing plus chlorhexidine) oral care on the development of ventilator-associated pneumonia in critically ill patients receiving mechanical ventilation. METHODS Cr...

AIM To evaluate the effect of different mouth rinses 12 h after rinsing on genuine intra-oral halitosis. MATERIALS AND METHODS Twenty-four adults with halitosis were included in a double-blind, crossover, randomized clinical trial. Halitosis was evaluated 12 h after rinsing with placebo and five mouth rinse products containing zinc acetate and chlorhexidine diacetate; zinc lactate, chlorhexid...