OBJECTIVE To determine the efficacy of supplementation with oral vitamin D₃ (cholecalciferol) on bone mineral biochemical parameters of school-going girls. SETTING Government school (government-aided) and Private school (fee paying) in Delhi. DESIGN Randomized controlled trial. INTERVENTION Cholecalciferol granules (60,000 IU) orally with water, either once in two months (two-monthly D₃ g...

BACKGROUND Vitamin D does not only regulate calcium homeostasis but also plays an important role as an immune modulator. It influences the immune system through the induction of immune shifts and regulatory cells resulting in immunologic tolerance. As such, vitamin D is thought to exert beneficial effects within the transplant setting, especially in kidney transplant recipients, considering the...

The importance of cholecalciferol in calcium absorption is well established, but the manner in which the vitamin exerts its effect at a molecular level is still unclear. The active form of cholecalciferol in the intestine is a steroid hormone 1,25-dihydroxycholecalciferol, which is known to be necessary for calcium absorption and the synthesis of the cytoplasmic calcium-binding protein (Lawson ...

BACKGROUND Previous studies have shown that treatment with ergocalciferol in patients with CKD stage 3 + 4 is not effective with less than 33% of patients achieving a 25-OH vitamin D target of >30 ng/ml. The aim of this study was to test the response to cholecalciferol in CKD. We attempted to replete 25-OH vitamin D to a target level of 40-60 ng/ml using the response to treatment and PTH suppre...

The publication focuses on the presentation of role vitamin D3 in human body. content contains important information influence course Covid-19 disease caused by Sars-Cov-19 virus. Cholecalciferol has been studied for years. Its basic functions include regulation bone mineral metabolism and calcium-phosphorus metabolism. In addition, characterizes synthesis presents Additionally, currently condu...

An 8 1/2-year-old girl presented with rickets. This had developed despite a normal diet and in the absence of symptoms, signs, or laboratory evidence of malabsorption, hepatic or renal disease. The rickets healed with physiological doses of 1-alpha-hydroxy-cholecalciferol. It is suggested that this case provides evidence for genetic and metabolic heterogeneity in vitamin D-dependent rickets.

Introduction: Vitamin D is produced under the influence of solar radiation. It can also be supplied in food or dietary supplements. The assessment total serum 25(OH)D widely accepted as an indicator vitamin concentration and observation population regarding hypovitaminosis recommendations supplementation. In fact, definition deficiency still a contentious issue, however, epidemiological data in...