Chronic granulomatous disease is a rare primary immunodeficiency caused by phagocytic cell defect. We describe the case of 43-month-old boy with chronic granulomatous disease presenting with Salmonella spp brain abscesses, together with a review of the 13 cases reported in the literature.

To directly examine the role of hydrogen peroxide in the killing of bacteria after ingestion by granulocytes, we have studied some of the events of phagocytosis of a mutant strain of pneumococci which is relatively deficient in peroxide production. The hydrogen peroxide-deficient pneumococci and the otherwise identical wild type were grown with [(14)C]arachidonic and [(3)H]palmitic acid labels ...

Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent, life-threatening bacterial and fungal infections of the skin, airways, lymph nodes, liver, brain, bones. These most commonly occur in organs contact with outside world (lungs, gastrointestinal tract, skin), as well nodes that drain these structures. While involvement can be seen many organs, there no k...

Granulomatous gastritis (GG) is a subtype of chronic which may be infectious, non-infectious, or idiopathic in nature. For treating clinicians, granulomatous has always been diagnostic challenge because the same clinical and endoscopic features between Crohn’s disease tuberculosis. A diagnosis can reached only by combination histopathological examination with laboratory investigations. Several ...